Question 1

Which of the following best describes the role of FAD in the citric acid cycle?

Accepted Answer

FAD is reduced to FADH2 during the oxidation of succinate to fumarate.

Question 2

Which step in glycolysis is directly responsible for the net production of ATP via substrate-level phosphorylation?

Accepted Answer

Step 7: 1,3-bisphosphoglycerate to 3-phosphoglycerate

Question 3

Given the following reaction: $$\Delta G_1$ = +3.3\ \mathrm{kcal/mol}$$ and $$\Delta G_2$ = -7.5\ \mathrm{kcal/mol}$$, what is the total $$\Delta G$$ for the coupled reaction?

Accepted Answer

$$-4.2\ \mathrm{kcal/mol}$$

Question 4

Which of the following reactions in the citric acid cycle is an example of a beta decarboxylation?

Accepted Answer

Conversion of alpha-ketoglutarate to succinyl-CoA

Question 5

During aerobic metabolism, what is the fate of pyruvate produced from glycolysis?

Accepted Answer

It is transported into the mitochondria and converted to acetyl-CoA.

Question 6

Which complex of the electron transport chain is responsible for reducing O$$_2 to H$_2O$$?

Accepted Answer

Complex IV (cytochrome c oxidase)

Question 7

Which of the following steps in glycolysis consumes ATP?

Accepted Answer

Step 1: Glucose to glucose-6-phosphate

Question 8

If a monosaccharide undergoes reduction, what is the resulting product?

Accepted Answer

An alditol

Question 9

Which of the following best describes the process occurring at ATP synthase (proton translocating ATPase) in the mitochondria?

Accepted Answer

It uses the proton gradient to synthesize ATP from ADP and inorganic phosphate.

Question 10

Which of the following is the correct net ATP yield from complete aerobic metabolism of one molecule of glucose?

Accepted Answer

$$36$$ ATP

Question 11

Which reaction in glycolysis involves a keto-enol tautomerization?

Accepted Answer

Step 10: Phosphoenolpyruvate to pyruvate

Question 12

Which of the following is produced during the conversion of isocitrate to alpha-ketoglutarate in the citric acid cycle?

Accepted Answer

NADH and CO$$_2$$

Question 13

Which of the following best describes the formation of a disaccharide with an $$\alpha-1$$,4-glycosidic bond?

Accepted Answer

The anomeric carbon of one sugar forms a bond with the fourth carbon of another sugar, with the glycosidic bond in the $$\alpha$$ configuration.

Question 14

Which of the following steps in the citric acid cycle directly produces GTP?

Accepted Answer

Conversion of succinyl-CoA to succinate

Question 15

Which of the following is true about the oxidation of monosaccharides to uronic acids?

Accepted Answer

The primary alcohol group at C-6 is oxidized to a carboxylic acid.

Question 16

Which of the following best describes what happens to pyruvate in yeast cells under anaerobic conditions?

Accepted Answer

It is converted to ethanol and CO$$_2.$$

Question 17

Which of the following glycolysis steps is an example of an Aldol cleavage?

Accepted Answer

Step 4: Fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate

Question 18

Which of the following is reduced during the oxidation of malate to oxaloacetate in the citric acid cycle?

Accepted Answer

NAD$$^+$$

Question 19

Which of the following best describes the formation of a phosphate ester from a monosaccharide?

Accepted Answer

A phosphate group is added to a hydroxyl group of the sugar.

Question 20

Which of the following steps in glycolysis produces NADH?

Accepted Answer

Step 6: Glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate

Study Guide: Biochemical Energy, Carbohydrates, and Carbohydrate Metabolism (Ch. 20, 21, 22.1-6)

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