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Comprehensive Microbiology Study Guide: Key Concepts and Exam Review

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Introduction to Cultivating Microbial Growth

  • Map of Techniques for Cultivating Microbes
    02:05
  • Introduction to Cultivating Microbial Growth
    03:49

Types of Solid Culture Media

  • Types of Solid Culture Media
    03:16

Plating Methods

  • Streak-Plate Method
    05:16
  • Spread-Plate Method vs. Pour-Plate Method
    05:36

Prokaryotic Ribosomes

  • Prokaryotic Ribosomes
    01:51
  • Structure of Prokaryotic Ribosomes
    08:39

Introduction to Taxonomy

  • Introduction to Taxonomy Example 2
    01:37
  • Categorizing Life Based on Energy Acquisition
    06:14
  • Introduction to Taxonomy
    02:23

Scientific Naming of Organisms

  • Scientific Naming of Organisms
    05:22

Magnification, Resolution, & Contrast

  • Magnification, Resolution, & Contrast
    07:29

Gram Stain

  • Gram Stain
    04:57

Introduction to Bacterial Cell Walls

  • Peptidoglycan
    01:58
  • Types of Bacterial Cell Walls
    02:44
  • Peptidoglycan Structure
    04:44

Gram-Negative Cell Walls

  • Gram-Negative Cell Walls
    3:04
  • Porins
    02:18
  • The Outer Membrane
    02:15

Bacterial Cell Morphology & Arrangements

  • Types of Bacterial Cell Morphology
    02:44
  • Bacterial Cell Morphology & Arrangements
    01:13
  • Bacilli Bacterial Cell Arrangements
    03:56

Fimbriae & Hami

  • Fimbriae & Hami
    01:52
  • Hami
    01:51

Introduction to Prokaryotic Flagella

  • Types of Flagellar Distribution on Bacteria
    05:22
  • Introduction to Prokaryotic Flagella
    02:07

Introduction to Bacterial Plasmids

  • Episomes
    01:47
  • Introduction to Bacterial Plasmids
    02:52

Binary Fission

  • Binary Fission
    02:16
  • Steps of Binary Fission
    04:57

Introduction to DNA-Based Technology

  • Map of DNA-Based Technology Lesson
    03:12
  • Introduction to DNA-Based Technology
    02:30

Introduction to DNA Cloning

  • Introduction to DNA Cloning
    02:25
  • Cloning with Recombinant DNA
    03:41

Introduction to Polymerase Chain Reaction

  • Introduction to Polymerase Chain Reaction
    01:31
  • Components of a Polymerase Chain Reaction
    05:57
  • Why do we use PCR?
    02:53

The Steps of PCR

  • 1) Denaturation
    03:33
  • 2) Annealing
    02:56
  • The Steps of PCR
    04:39

Central Dogma

  • Central Dogma
    05:45

Introduction to Transcription

  • Overview of Transcription
    07:44
  • Introduction to Transcription
    05:51

Steps of Transcription

  • Elongation of Transcription
    02:44
  • Initiation of Transcription
    04:16
  • Elongation of Transcription
    04:01

Introduction to Translation

  • Ribosomal tRNA Binding Sites
    06:16
  • Ribosome Subunits
    08:42
  • Introduction to Translation
    06:12

Steps of Translation

  • Elongation of Translation
    04:59
  • Termination of Translation
    02:16
  • Steps of Translation
    05:03

Introduction to Mutations

  • Spontaneous vs. Induced Mutations
    02:47
  • Introduction to Mutations
    00:37
  • Types of Mutations
    08:44

Introduction to DNA Repair

  • Introduction to DNA Repair
    02:47

DNA Repair Mechanisms

  • Nucleotide Excision Repair
    03:31
  • SOS Repair System
    03:50
  • Photoreactivation
    02:29

Horizontal Gene Transfer

  • Fates of Horizontally Transferred DNA
    03:13
  • Horizontal Gene Transfer
    04:42
  • Integration of DNA via Homologous Recombination
    02:52

Bacterial Transformation

  • Bacterial Transformation
    03:06
  • Mechanism of Natural Transformation
    03:49

Transduction

  • Generalized Transduction
    04:24
  • Transduction
    06:49
  • Specialized Transduction
    06:34

Introduction to Conjugation

  • Introduction to Conjugation
    04:21

Conjugation: F Plasmids

  • F Plasmids
    05:57
  • Mechanism of F Plasmid Conjugation in E. coli
    04:12

Conjugation: Hfr & F' Cells

  • F’ Cell Conjugation
    04:31
  • Hfr Cell Conjugation
    09:41

Introduction to Controlling Microbial Growth

  • Terminology of Microbial Growth Control
    07:36
  • Hierarchy of Microbial Growth Control Terminology
    03:09
  • Situations Warranting Different Levels of Microbial Growth Control
    05:58

Physical Methods to Control Microbial Growth

  • Dry Heat
    02:58
  • Irradiation
    06:18
  • Filtration
    04:29

Chemical Methods to Control Microbial Growth

  • Types of Disinfectants
    05:21
  • Selecting the Right Chemical Agent
    04:52
  • Chemical Methods to Control Microbial Growth
    03:58

Chemicals Used to Control Microbial Growth

  • Chemicals Used to Control Microbial Growth
    02:29
  • Factors Affecting Chemical Agents
    03:17

Liquid Chemicals: Alcohols, Aldehydes, & Biguanides

  • Alcohols
    03:39
  • Biguanides
    02:41
  • Aldehydes
    03:59

Liquid Chemicals: Halogens

  • Iodine
    02:15
  • Chlorine
    03:16
  • Liquid Chemicals: Halogens
    00:56

Liquid Chemicals: Surface-Active Agents

  • Liquid Chemicals: Surface-Active Agents
    04:14
  • Soaps & Detergents
    06:20
  • Quats
    02:33

Chemical Gases: Ethylene Oxide, Ozone, & Formaldehyde

  • Ozone
    02:36
  • Formaldehyde Gas
    02:56
  • Chemical Gases: Ethylene Oxide
    03:22

Symbiotic Relationships

  • Symbiotic Relationships
    05:59

The Human Microbiome

  • The Human Microbiome
    03:25
  • Microbiome Promotes Immune Tolerance
    05:48
  • Microbiome Makes Nutrients & Aids in Host Digestion
    03:26

Characteristics of Infectious Disease

  • Primary vs. Secondary Infections
    04:16
  • Communicable vs. Noncommunicable Diseases
    04:57
  • Intro to Characteristics of Infectious Disease
    05:09

Stages of Infectious Disease Progression

  • Stages of Infectious Disease Progression
    05:36
  • Chronic & Latent Infection Disease Progression
    05:14

Koch's Postulates

  • Koch's Postulates
    01:36
  • The 4 Koch's Postulates
    03:31
  • Limitations to Koch's Postulates
    02:58

Molecular Koch's Postulates

  • The 3 Molecular Koch's Postulates
    03:20
  • Intro to Molecular Koch's Postulates
    01:32

Bacterial Pathogenesis

  • Intro to Bacterial Pathogenesis
    02:35
  • 1) Exposure to Pathogen
    03:27
  • 3) Invasion into Host Tissues
    05:38

Introduction to Pathogenic Toxins

  • Introduction to Pathogenic Toxins
    03:40

Exotoxins Cause Damage to the Host

  • 1) A-B Toxins
    04:44
  • Types of Exotoxins
    03:30
  • 3) Superantigens
    03:59

Endotoxin Causes Damage to the Host

  • Endotoxin
    02:46
  • Lipid A Causes Septic Shock
    03:24

Exotoxins vs. Endotoxin Review

  • Exotoxins vs. Endotoxin Review
    07:22

Immune Response Damage to the Host

  • Inflammatory Response Can damage the Host
    03:31
  • Intro to Immune Response Damage
    02:57
  • Adaptive Immunity Can Damage the Host
    03:22

Introduction to Avoiding Host Defense Mechanisms

  • Introduction to Avoiding Host Defense Mechanisms
    01:59

1) Hide Within Host Cells

  • Hide Within Host Cells
    01:50

2) Avoiding Phagocytosis

  • Pathogen Use Capsules & M Proteins to Avoid Opsonization
    05:25
  • Pathogens Avoid Encounter with Phagocytes
    05:13
  • Pathogens Use Fc Receptors to Prevent Opsonization
    03:48

3) Surviving Inside Phagocytic Cells

  • Surviving Inside Phagocytic Cells
    04:18

4) Avoiding Complement System

  • Avoiding Complement System
    04:53

5) Avoiding Antibodies

  • Bacteria Avoid Antibodies by Producing IgA Proteases
    02:59
  • Bacteria Avoid Immune System by Mimicking Host Molecules
    03:11
  • Intro to Avoiding Antibodies
    01:35

Viruses Evade the Immune Response

  • 3) Viruses Avoid the Effects of Antibodies
    3:57
  • Intro to How Viruses Evade the Immune Response
    02:13
  • 2) Viruses Interfere with Antigen Presentation in Infected Cells
    3:43

Introduction to Immunity

  • Innate vs. Adaptive Immunity
    05:52
  • Antigens & Antibodies
    02:58

Introduction to Innate Immunity

  • Introduction to Innate Immunity
    02:30
  • Map of Lesson on Innate Immunity
    06:42

Introduction to First-Line Defenses

  • Introduction to First-Line Defenses
    01:56
  • Map of the Lesson on First-Line Defenses
    01:37

Physical Barriers in First-Line Defenses: Skin

  • Physical Barriers in First-Line Defenses: Skin
    01:28
  • Physical Barriers in First-Line Defenses: Skin
    04:08

Physical Barriers in First-Line Defenses: Mucous Membrane

  • Peristalsis & Mucociliary Escalator
    04:16
  • Mucous Membranes
    02:34

First-Line Defenses: Chemical Barriers

  • Chemical Defenses: Gastric Juice Prevents Microbial Growth by Lowering pH
    02:07
  • Chemical Defenses: Earwax Prevents Microbial Growth by Controlling pH
    02:18
  • Chemical Defenses: Sweat Glands Prevent Microbial Growth by Perspiration
    02:04

First-Line Defenses: Normal Microbiota

  • Normal Microbiota
    03:43

Introduction to Cells of the Immune System

  • Introduction to Cells of the Immune System
    03:27
  • Map of the Lesson on Cells of the Immune System
    06:08
  • Hematopoiesis
    02:33

Cells of the Immune System: Granulocytes

  • Granulocytes
    03:32
  • Neutrophils
    05:32
  • Basophils
    03:23

Cells of the Immune System: Agranulocytes

  • Monocytes
    07:16
  • Introduction to Lymphocytes
    03:51
  • Agranulocytes
    03:43

Introduction to Cell Communication

  • Introduction to Cell Communication
    02:59

Cell Communication: Surface Receptors & Adhesion Molecules

  • Cell Surface Receptors
    04:05
  • Adhesion Molecules
    02:58

Cell Communication: Cytokines

  • Cytokines
    02:59
  • Types of Cytokines
    06:08
  • Types of Interleukins
    02:14

Pattern Recognition Receptors (PRRs)

  • Pattern Recognition Receptors
    04:24
  • C-Type Lectin Receptors
    02:46
  • Retinoic acid Inducible Gene (RIG)-Like Receptors
    04:02

Introduction to the Complement System

  • Map of the Lesson on the Complement System
    03:25
  • Introduction to the Complement System
    04:25
  • Proteins of the Complement System
    04:16

Activation Pathways of the Complement System

  • 2) Lectin Pathway
    03:04
  • 1) Alternative Pathway
    04:40
  • 3) Classical Pathway
    03:42

Effects of the Complement System

  • 1) Opsonization
    04:09
  • 2) Cell Lysis of Invading Microbes
    03:18
  • Effects of the Complement System
    01:32

Review of the Complement System

  • Review of the Complement System
    05:15

Phagoctytosis

  • Steps of Phagocytosis
    08:57
  • Phagoctytosis
    02:19

Introduction to Inflammation

  • Types of Inflammatory Responses
    02:52
  • Introduction to Inflammation
    01:38
  • Chronic Inflammation
    03:09

Steps of the Inflammatory Response

  • 2) Release of Inflammatory Mediators & Other Cytokines
    02:15
  • Damaging Effects of the Inflammatory Response
    02:10
  • 3) Vasodilation
    02:39

Fever

  • Fever
    03:57

Interferon Response

  • Interferon Response
    01:32
  • Steps of the Interferon Response
    09:59

Introduction to Adaptive Immunity

  • Overview of Adaptive Immunity
    04:57
  • Primary vs. Secondary Lymphoid Organs
    04:58
  • Introduction to Adaptive Immunity
    05:47

Antigens

  • Free Antigens vs. Presented Antigens on APCs
    04:11
  • Antigens
    03:59

Introduction to T Lymphocytes

  • Cytotoxic T Cells vs. Helper T Cells
    05:58
  • T-Cell Receptors
    05:18
  • Naive T Cells Become Effector & Memory T Cells
    07:56

Major Histocompatibility Complex Molecules

  • Classes of MHC Molecules
    07:17
  • Major Histocompatibility Complex Molecules
    02:31

Activation of T Lymphocytes

  • Activation of T Lymphocytes
    07:33
  • Comic Strip for T Cell Activation
    03:29

Functions of T Lymphocytes

  • Functions of Helper T Cells (TH):Activation of Macrophages
    05:18
  • Types of Helper T Cells (TH)
    03:19
  • Functions of Cytotoxic T Cells (Tc)
    06:21

Review of Cytotoxic vs Helper T Cells

  • Review of Cytotoxic vs Helper T Cells
    04:27
  • Comic Strip for T Cell Functions
    02:58

Introduction to B Lymphocytes

  • B cell Receptors
    04:37
  • Naive B cells Become Effector (Plasma) Cells & Memory Cells
    04:23
  • Introduction to B Lymphocytes
    03:55

Antibodies

  • Antibody Structure
    05:40
  • Antibody Diversity
    02:34
  • Antibodies
    00:48

Classes of Antibodies

  • IgE
    02:45
  • IgA
    02:44
  • Classes of Antibodies
    04:43

Outcomes of Antibody Binding to Antigen

  • Outcomes of Antibody Binding to Antigen
    09:16

T Dependent & T Independent Antigens

  • B Cell Activation by T Dependent Antigens
    05:09
  • T Dependent & T Independent Antigens
    02:08
  • B Cell Activation by T Independent Antigens
    03:11

Clonal Selection

  • Clonal Selection
    06:43

Antibody Class Switching

  • Antibody Class Switching
    07:52

Affinity Maturation

  • Affinity Maturation
    07:27

Primary and Secondary Response of Adaptive Immunity

  • Primary and Secondary Response of Adaptive Immunity
    06:59

Immune Tolerance

  • Central vs. Peripheral Tolerance
    11:54
  • Immune Tolerance
    03:19
  • Football Analogy for Immune Tolerance
    03:21

Regulatory T Cells

  • Regulatory T Cells
    03:53

Natural Killer Cells

  • Natural Killer Cells
    06:53

Review of Adaptive Immunity

  • Review of Adaptive Immunity
    09:20