Scientific Naming of Organisms
Members of the Bacterial World
Introduction to Microbiology
Introduction to Spontaneous Generation
Francesco Redi's Experiments
Needham vs. Spallanzani
Pasteur's Experiments on Spontaneous Generation
Koch's Postulates
Introduction to Microscopes
Magnification, Resolution, & Contrast
Introduction to Light Microscopy
Light Microscopy: Bright-Field Microscopes
Light Microscopes that Increase Contrast
Light Microscopes that Detect Fluorescence
Electron Microscopes
Reviewing the Different Types of Microscopes
Introduction to Staining
Simple Staining
Differential Staining
Gram Stain
Other Types of Staining
Reviewing the Types of Staining
Prokaryotic & Eukaryotic Cells
Bacterial & Eukaryotic Cell Membranes
Overview of Prokaryotic Cell Structure
Bacterial Cell Morphology & Arrangements
The Glycocalyx: Capsules & Slime Layers
Introduction to Prokaryotic Flagella
Fimbriae & Hami
Pili
Introduction to Bacterial Cell Walls
Gram-Positive Cell Walls
Gram-Negative Cell Walls
Gram-Positive vs. Gram-Negative Cell Walls
Endospores
Introduction to Eukaryotic Organelles
Endosymbiotic Theory
Introduction to Membrane Transport
Passive vs. Active Transport
Osmosis
Simple and Facilitated Diffusion
Active Transport
Group Translocation
Introduction to Metabolism
Enzymes
Redox Reactions
Glycolysis
Krebs Cycle
Electron Transport Chain
Fermentation & Anaerobic Respiration
Temperature Requirements for Microbial Growth
pH Requirements for Microbial Growth
Osmolarity Factors for Microbial Growth
Nutritional Factors of Microbial Growth
Oxygen Requirements for Microbial Growth
Biofilms
Introduction to Cultivating Microbial Growth
Types of Solid Culture Media
Chemically Defined Media
Complex Media
Reducing Media
Selective Media
Differential Media
Enrichment Media
Plating Methods
Growing a Pure Culture
Binary Fission
Generation Times
Microbial Growth Curves in a Closed System
Measuring Growth by Direct Cell Counts
Measuring Growth by Plate Counts
Measuring Growth by Membrane Filtration
Measuring Growth by Biomass
Introduction to Controlling Microbial Growth
Selecting a Method to Control Microbial Growth
Physical Methods to Control Microbial Growth
Chemical Methods to Control Microbial Growth
Central Dogma
Introduction to DNA Replication
Introduction to Transcription
Genetic Code
Introduction to Types of RNA
Introduction to Translation
Prokaryotic Gene Expression
Introduction to Regulation of Gene Expression
Prokaryotic Gene Regulation via Operons
The Lac Operon
Introduction to Mutations
Methods of Inducing Mutations
Prototrophs vs. Auxotrophs
Mutant Detection
The Ames Test
Introduction to Microbial Genetics
Horizontal Gene Transfer
Bacterial Transformation
Introduction to Conjugation
Conjugation: F Plasmids
Conjugation: Hfr & F' Cells
Transduction
Introduction to Viruses
Plaque Assays
Introduction to Animal Virus Infections
Bacteriophage: Lytic Phage Infections
Bacteriophage: Lysogenic Phage Infections
Animal Viruses: 1. Attachment to the Host Cell
Animal Viruses: 2. Entry & Uncoating in the Host Cell
Animal Viruses: 3. Synthesis & Replication
Animal Viruses: DNA Virus Synthesis & Replication
Animal Viruses: RNA Virus Synthesis & Replication
Acute vs. Persistent Viral Infections
Viroids
Prions
Symbiotic Relationships
The Human Microbiome
Characteristics of Infectious Disease
Stages of Infectious Disease Progression
Reservoirs of Infection
Disease Transmission
Healthcare-Associated Infections
Emerging Infectious Diseases
Introduction to Epidemiology
Factors Influencing Epidemiology
Epidemiological Studies
Bacterial Pathogenesis
Introduction to Avoiding Host Defense Mechanisms
Introduction to Pathogenic Toxins
Exotoxins Cause Damage to the Host
Endotoxin Causes Damage to the Host
Exotoxins vs. Endotoxin Review
Viruses Evade the Immune Response
Introduction to Immunity
Introduction to Innate Immunity
Introduction to First-Line Defenses
Physical Barriers in First-Line Defenses: Skin
Physical Barriers in First-Line Defenses: Mucous Membrane
First-Line Defenses: Chemical Barriers
First-Line Defenses: Normal Microbiota
Introduction to Cells of the Immune System
Cells of the Immune System: Granulocytes
Cells of the Immune System: Agranulocytes
Phagoctytosis
Cell Communication: Surface Receptors & Adhesion Molecules
Introduction to Inflammation
Steps of the Inflammatory Response
Fever
Introduction to the Complement System
Activation Pathways of the Complement System
Effects of the Complement System
Review of the Complement System
Interferon Response
Introduction to Adaptive Immunity
Cell Communication: Cytokines
Antigens
Antibodies
Classes of Antibodies
Outcomes of Antibody Binding to Antigen
Major Histocompatibility Complex Molecules
T Dependent & T Independent Antigens
Introduction to T Lymphocytes
Review of Cytotoxic vs Helper T Cells
Introduction to B Lymphocytes
Clonal Selection
Affinity Maturation
Activation of T Lymphocytes
Functions of T Lymphocytes
Regulatory T Cells
Natural Killer Cells
Primary and Secondary Response of Adaptive Immunity
Review of Adaptive Immunity
Types of Acquired Immunity
Introduction to Vaccines
Attenuated Vaccines
Inactivated Vaccines
Immunotherapy: Monoclonal Antibodies
Immunoassay: Fluorescent Antibody Tests
Immunoassay: ELISA
Immunoassay: Western Blotting
Introduction to Hypersensitivites
Type I Hypersensitivities
Type IV Hypersensitivities
Reviewing the 4 Types of Hypersensitivities
Autoimmune Diseases
Immunodeficiency Disorders
Introduction to Antimicrobial Drugs
Broad vs Narrow Spectrum Drugs
How Antimicrobial Drugs Work
Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin
Inhibitors of Protein Synthesis
Disruptors of Cell Membranes
Inhibitors of Nucleic Acid Synthesis
Competitive Inhibitors of Metabolic Pathways
Antifungal Drugs
Antiviral Drugs
Tests to Guide Antimicrobial Use
Antimicrobial Resistance
Therapeutic Window & Therapeutic Index
Drug Interactions: Synergism and Antagonism