The only genus of Gram-negative cocci that causes significant disease in humans is
a. Pasteurella
b. Salmonella
c. Klebsiella
d. Neisseria

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Understand the question is asking for the genus of Gram-negative cocci that is medically significant in humans.

Recall that Gram-negative bacteria are classified by shape: cocci (spherical), bacilli (rod-shaped), etc.

Identify which of the listed genera are Gram-negative cocci: Pasteurella, Salmonella, Klebsiella, and Neisseria.

Recognize that Pasteurella, Salmonella, and Klebsiella are Gram-negative rods, not cocci.

Know that Neisseria is the only genus among the options that consists of Gram-negative cocci and includes important human pathogens like Neisseria gonorrhoeae and Neisseria meningitidis.

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Gram-negative Cocci

Gram-negative cocci are spherical bacteria that do not retain the crystal violet stain during Gram staining, appearing pink under a microscope. They are less common than Gram-positive cocci and include genera like Neisseria, which are important in human disease.

Pathogenic Genera of Gram-negative Bacteria

Among Gram-negative bacteria, certain genera are known for causing human diseases. While many are rod-shaped (bacilli), only a few cocci genera, notably Neisseria, are significant pathogens, causing diseases such as meningitis and gonorrhea.

Neisseria as a Human Pathogen

Neisseria is the only genus of Gram-negative cocci that includes species causing major human diseases, like Neisseria meningitidis (meningitis) and Neisseria gonorrhoeae (gonorrhea). Its unique pathogenicity distinguishes it from other Gram-negative bacteria.

The only genus of Gram-negative cocci that causes significant disease in humans isa. Pasteurellab. Salmonellac. Klebsiellad. Neisseria