Skip to main content
Ch. 12 - Adaptive Immunity
Norman-McKay- Microbiology: Basic and Clinical Principles 2nd Edition
Norman-McKay2nd EditionMicrobiology: Basic and Clinical PrinciplesISBN: 9780137661619당신이 사용하는 게 아니라요?교과서 변경
8장, 문제 2

In which of the following scenarios would administering immunoglobulins be useful? Select all that apply. (NCLEX/HESI/TEAS)
a. To neutralize a toxin
b. To aid a patient who is immune compromised
c. After venom exposure
d. To block IgM from crossing the placenta
e. To protect a premature infant from respiratory syncytial virus

검증된 단계별 안내
1
Step 1: Understand what immunoglobulins are and their primary function. Immunoglobulins (antibodies) are proteins produced by the immune system that recognize and neutralize pathogens such as bacteria, viruses, and toxins.
Step 2: Analyze each scenario to determine if passive immunity via immunoglobulin administration would be beneficial. Passive immunity involves giving pre-formed antibodies to provide immediate protection or neutralization.
Step 3: For option (a) 'To neutralize a toxin' — immunoglobulins can bind to toxins and neutralize them, so administering immunoglobulins is useful here.
Step 4: For option (b) 'To aid a patient who is immune compromised' — immunoglobulins can provide passive immunity to patients who cannot mount an effective immune response, making this a valid use.
Step 5: For options (c) 'After venom exposure' and (e) 'To protect a premature infant from respiratory syncytial virus' — immunoglobulins specific to venom or RSV can be administered to neutralize venom or protect vulnerable infants, so these are also appropriate uses. Option (d) 'To block IgM from crossing the placenta' is not a typical use of immunoglobulins, as IgM does not cross the placenta significantly.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
3m

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Passive Immunization with Immunoglobulins

Passive immunization involves administering pre-formed antibodies (immunoglobulins) to provide immediate but temporary protection against specific pathogens or toxins. It is useful in situations where rapid immunity is needed, such as toxin neutralization or post-exposure prophylaxis.
추천 영상:
05:05
Passive vs. Active Transport

Indications for Immunoglobulin Therapy

Immunoglobulin therapy is indicated for neutralizing toxins (e.g., tetanus), treating immune-compromised patients who cannot produce adequate antibodies, and providing protection after exposure to certain venoms or viruses. It is not used to block antibody transfer across the placenta.
추천 영상:
03:48
Review Table of Immunoglobin Classes

Limitations of Immunoglobulin Use

Immunoglobulins do not prevent the natural transfer of maternal IgG across the placenta and are not designed to block IgM. Their protection is temporary, and they do not replace active immunization or long-term immunity, especially in premature infants who may require additional interventions.
추천 영상:
02:58
Limitations to Koch's Postulates