A drug that binds to mannose on human cells would prevent
a. the entrance of Vibrio enterotoxin.
b. the attachment of pathogenic E. coli.
c. the action of botulinum toxin.
d. streptococcal pneumonia.
e. the action of diphtheria toxin.

검증된 단계별 안내

Step 1: Understand the role of mannose in microbial pathogenesis. Mannose residues on human cell surfaces often serve as binding sites for certain bacteria or their toxins, facilitating attachment or entry.

Step 2: Identify which pathogens or toxins specifically interact with mannose residues. For example, some pathogenic strains of Escherichia coli use mannose-sensitive fimbriae (pili) to attach to host cells.

Step 3: Analyze each option in the question to determine if the pathogen or toxin binds to mannose on human cells. For instance, Vibrio enterotoxin and botulinum toxin do not typically bind mannose; their mechanisms differ.

Step 4: Recognize that preventing binding to mannose would block the initial attachment step for pathogens that rely on mannose-mediated adhesion, such as certain pathogenic E. coli strains.

Step 5: Conclude that a drug binding to mannose would most likely prevent the attachment of pathogenic E. coli, as this bacterium uses mannose-sensitive adhesion to colonize host cells.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.

영상 길이:

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Role of Mannose in Bacterial Adhesion

Mannose residues on human cell surfaces serve as binding sites for certain bacterial adhesins, facilitating attachment. Pathogenic bacteria like some strains of E. coli use mannose-specific fimbriae to adhere to host cells, initiating infection. Blocking mannose can prevent this attachment, hindering colonization.

Mechanism of Bacterial Toxins

Bacterial toxins such as enterotoxins, botulinum, and diphtheria toxins have distinct modes of action, often independent of mannose binding. For example, botulinum toxin inhibits neurotransmitter release, while diphtheria toxin inhibits protein synthesis. Understanding these mechanisms helps differentiate toxin effects from adhesion processes.

Pathogenesis of Vibrio and Streptococcal Infections

Vibrio enterotoxins cause diarrhea by disrupting ion transport in intestinal cells, but their entry does not rely on mannose binding. Streptococcal pneumonia involves bacterial colonization and immune evasion mechanisms unrelated to mannose-mediated adhesion. Recognizing these differences clarifies which pathogens are affected by mannose-binding drugs.

A drug that binds to mannose on human cells would preventa. the entrance of Vibrio enterotoxin.b. the attachment of pathogenic E. coli.c. the action of botulinum toxin.d. streptococcal pneumonia.e. the action of diphtheria toxin.