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Ch. 19 - Disorders Associated with the Immune System
Tortora - Microbiology: An Introduction 14th Edition
Tortora14th EditionMicrobiology: An IntroductionISBN: 9780138200398당신이 사용하는 게 아니라요?교과서 변경
15장, 문제 1

Desensitization to prevent an allergic response can be accomplished by injecting small, repeated doses of:
a. IgE antibodies
b. The antigen (allergen)
c. Histamine
d. IgG antibodies
e. Antihistamine

검증된 단계별 안내
1
Understand the concept of desensitization in allergy treatment: it involves gradually exposing the immune system to increasing amounts of the allergen to build tolerance and reduce allergic reactions.
Recall that desensitization is typically done by injecting small, repeated doses of the allergen itself, not antibodies or histamine, to modify the immune response.
Recognize that injecting IgE antibodies would worsen the allergic response since IgE mediates allergy symptoms, so this is not used for desensitization.
Note that injecting histamine or antihistamines directly is not a method of desensitization; histamine causes symptoms, and antihistamines block symptoms but do not induce tolerance.
Conclude that the correct approach is injecting small, repeated doses of the antigen (allergen) to safely train the immune system to become less reactive.

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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Allergic Response and IgE Antibodies

An allergic response is triggered when IgE antibodies recognize an allergen, leading to the release of histamine and other chemicals from mast cells. This causes symptoms like inflammation and itching. Understanding the role of IgE is crucial to grasp how allergies develop and how they can be modulated.
추천 영상:

Desensitization (Allergen Immunotherapy)

Desensitization involves administering gradually increasing doses of the allergen to the patient. This process helps the immune system develop tolerance, reducing the allergic reaction over time by shifting the immune response away from IgE-mediated pathways.
추천 영상:
가이드 코스
04:43
Classes of Antibodies

Role of IgG Antibodies in Allergy Treatment

IgG antibodies can block allergens from binding to IgE on mast cells, preventing allergic reactions. During desensitization, the immune system often produces more IgG, which acts as a 'blocking antibody' and contributes to the reduction of allergy symptoms.
추천 영상:
가이드 코스
03:48
Review Table of Immunoglobin Classes