how-would-you-design-a-synthetic-route-to-convert-a-chiral-compound-into-a-meso-

Question

How would you design a synthetic route to convert a chiral compound into a meso compound?

Accepted Answer

Introduce a symmetrical functional group to create an internal line of symmetry.

Answer

Remove all chiral centers.

Answer

Increase the molecular weight.

Answer

Add more chiral centers to the molecule.