when-designing-a-synthetic-analog-of-a-steroid-hormone-which-structural-feature-

Question

When designing a synthetic analog of a steroid hormone, which structural feature is most critical to retain for maintaining biological activity?

Accepted Answer

The specific stereochemistry of the hormone.

Answer

Presence of a hydroxyl group at any position.

Answer

The overall size of the molecule.

Answer

The presence of a carbonyl group at position 3.