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Advanced Organic Chemistry: Reactivity, Synthesis, and Heterocycles

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Nucleophilic Addition

  • Nucleophilic Addition
    08:27

Organometallics on Ketones

  • Nucleophilic Addition on Ketones and Aldehydes
    03:57
  • Organometallic on Aldehyde
    03:21

Ketone and Aldehyde Synthesis Reactions

    Protecting Alcohols from Organometallics

    • Use of Protecting Groups
      04:34
    • Provide mechanism and final product of transformation.
      04:45

    Enolate Alkylation and Acylation

    • Enolates of Esters
      03:05
    • General Reaction
      01:11
    • Directed Reactions
      04:35

    Conjugation Chemistry

    • Conjugated states
      03:27
    • Definition of Conjugation
      05:29
    • Review of Common Resonance Structures
      04:50

    Overview of Chemical Reactions

    • Recognizing Substitution Reactions.
      01:34
    • Recognizing Acid-Base Reactions.
      02:43
    • Recognizing Elimination Reactions.
      00:40

    Aromatic Heterocycles

    • Determine heterocycle aromaticity
      03:21
    • Heteroatoms
      03:21
    • Determine heterocycle aromaticity
      00:56

    Electrophilic Aromatic Substitution

    • EAS General Mechanism
      06:52
    • EAS Review
      03:07

    Nucleophilic Aromatic Substitution

    • The Meisenheimer Complex
      06:23
    • Which ipso-substitution is more favored
      03:30
    • General Mechanism
      06:45

    Retrosynthesis

    • Intro
      01:07