A college student wakes up several times at night to urinate after drinking wine because

transient suppression of vasopressin by alcohol leads to decreased aquaporin insertion and increased water excretion.

alcohol functions as a nonreabsorbable solute in the nephron, creating an osmotic gradient for water loss.

alcohol irreversibly impairs thick ascending limb countercurrent multiplication, reducing concentrating ability after a single exposure.

alcohol enhances insensible fluid losses (sweating, respiration), prompting compensatory nocturnal diuresis.