Based on Maslow's hierarchy of needs, if an adult's safety and physiological needs are chronically unmet, which of the following is most accurate about their ability to achieve self-actualization?

They can still reliably achieve self-actualization without addressing lower needs.

They will likely be unable to reach self-actualization until lower-level needs are substantially met.

They should first pursue esteem needs because esteem directly causes physiological stability.

They can skip lower needs by focusing on creative work alone and still reach self-actualization.