BackIntegumentary System and Dermatology: Medical Terminology Study Guide
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Dermatology and the Integumentary System
Introduction to Dermatology
Dermatology is the medical specialty focused on the anatomy, physiology, diseases, and treatments of the integumentary system, which includes the skin, nails, and subcutaneous tissue. Dermatologists utilize laboratory tests, diagnostic procedures, medical and surgical interventions, and pharmacological therapies to manage integumentary disorders.

Components of the Integumentary System
The integumentary system covers most of the body and is composed of the skin (the largest organ), nails, and subcutaneous tissue. Each component plays a vital role in protection, sensation, and homeostasis.

Anatomy of the Skin
Word Parts and Terminology
integument/o-: skin
-ary: pertaining to
cutane/o-: skin
-ous: pertaining to
Layers of the Skin
The skin consists of two primary layers:
Epidermis: The thin, outermost layer made of epithelial tissue. It contains both living and dead cells, with the surface cells filled with keratin for protection and waterproofing.
Dermis: The thick layer beneath the epidermis, composed of connective tissue, collagen, and elastin. It houses blood vessels, nerves, hair follicles, sebaceous glands, and sweat glands.

Epidermis Details
Squamous layer: Upper part, contains dead keratinized cells.
Basal layer: Deep part, contains living cells and melanocytes (produce melanin pigment).
Melanocytes: All individuals have the same number, but melanin production varies. Sun exposure increases melanin; insufficient absorption leads to sunburn.
Dermis Details
Contains collagen (firm, white protein) and elastin (elastic, yellow protein).
Includes arteries, veins, nerves, hair follicles, sebaceous glands, and sweat glands.
Dermatome: Area of skin sending sensory information to the spinal cord; also refers to a surgical instrument.
Glands of the Skin
Sebaceous glands: Oil glands producing sebum, which moisturizes skin and hair.
Sudoriferous glands: Sweat glands secreting sweat (water, sodium, waste) through skin pores.
Hair and Nails
Hair: Covers most of the body; color determined by melanocytes; strength from keratin.
Piloerection: Goosebumps caused by contraction of tiny muscles at hair follicle base.
Nails: Consist of nail plate, root, lunula, cuticle, and nail bed. Nail growth originates from the root, forming the lunula and hardening into the plate.

Subcutaneous Tissue
Loose connective tissue beneath the dermis, also called sub Q or subcu.
Composed of adipose (fatty) tissue and lipocytes.
Functions: Cushions, insulates, and protects internal organs; thickness varies with fat storage.
Physiology of the Integumentary System
Protection
First line of defense against injury and infection.
Acidic epidermis discourages microorganism growth.
Keratin waterproofs skin; sweat and sebum contain antibodies and enzymes.
Repair
Basal epidermal cells migrate to cover wounds.
Deep wounds form blood clots and scabs; new cells fill in the wound.
Sensation
Sensory receptors in the dermis detect touch, pressure, vibration, pain, and temperature.
Nervous system interprets skin sensations.
Vitamin D Synthesis
UV rays convert epidermal cholesterol to vitamin D.
Vitamin D aids calcium absorption; sun exposure requirements vary by skin tone.
Thermoregulation
Subcutaneous tissue stores fat and conserves heat.
Piloerector muscles contract to generate heat.
Sudoriferous glands produce sweat for cooling.
Dermal blood vessels dilate to release heat.

Homeostasis
Maintains balance and stability of body systems.
Thermoregulation is a key aspect.
Skin conditions can signal other medical issues.
Diseases and Disorders of the Skin
Edema
Edema is swelling caused by excess fluid in tissues. Pitting edema occurs when pressure leaves a deep indentation.

Types of Skin Lesions
Skin lesions are classified by appearance, contents, and cause. Common types include cysts, fissures, macules, papules, pustules, scales, vesicles, and wheals.
Lesion | Description | Color | Contents | Example |
|---|---|---|---|---|
Cyst | Elevated circular mound | Skin color or erythema | Semisolid or partly fluid filled | Acne sebaceous cyst |
Fissure | Small, cracklike crevice | Erythema | None, some fluid exudate | Dry, chapped skin |
Macule | Flat circle | Pigmented brown or black | None | Freckle, age spot |
Papule | Elevated | Skin color or erythema | Solid | Acne pimple |
Pustule | Elevated | White top | Pus | Acne whitehead |
Scale | Flat to slightly elevated, thin flake | White | None | Dandruff, psoriasis |
Vesicle | Elevated with pointed top | Erythema with transparent top | Clear fluid | Herpes, chickenpox, shingles |
Wheal | Elevated with broad, flat top | Erythema with pale top | Clear fluid | Insect bites, urticaria |

Skin Color Conditions
Insufficient melanin production leads to pale skin.
Cyanosis: Bluish discoloration due to lack of oxygen.
Necrosis: Tissue death from lack of blood supply.
Vitiligo: Autoimmune disorder causing depigmentation.

Skin Injuries
Burns: Partial-thickness burns cause separation of epidermis and dermis, leading to blisters.
Rule of Nines: Tool for estimating burn surface area.
Keloid: Excessive scar tissue formation.
Laceration: Deep cut exposing subcutaneous tissue.
Pressure injury: Caused by prolonged pressure, leading to tissue damage.

Skin Infections
Herpes simplex type 1: Vesicles on lips.
Shingles: Vesicles and crusts along a dermatome.
Tinea capitis: Fungal infection of the scalp, also known as ringworm.

Allergic Skin Conditions
Contact dermatitis: Skin reaction to irritants or allergens.

Benign Neoplasms of the Skin
Hemangioma: Bright red lesion from dilated blood vessels.
Nevus (mole): Pigmented, can be raised or flat, sometimes with hair.
Port-wine stain: Flat, red nevus resembling spilled wine.
Syndactyly: Fusion of skin and soft tissues between fingers or toes.

Malignant Neoplasms of the Skin
Malignant melanoma: Asymmetrical, irregular edges, varying color, increasing size.

Autoimmune Disorders of the Skin
Psoriasis: Commonly affects elbows and knees, characterized by red, scaly patches.

Diseases of the Sebaceous Glands
Acne vulgaris: Papules and pustules triggered by increased sebaceous gland activity.
Rosacea: Rose-colored erythema and dilated blood vessels, often affecting the face.

Diseases of the Nail
Onychomycosis: Fungal infection causing discoloration, thickening, and deformation of nails.
Laboratory, Diagnostic, Medical, and Surgical Procedures
Botox Injection
Botox is a diluted neurotoxin used for cosmetic and medical purposes.

Skin Examination
Dermatologists use magnifying lenses to examine skin lesions, sometimes requiring biopsy.

Wound Closure
Deep wounds may be closed with sutures or surgical glue.

Hypodermic Injection
Injection technique involves delivering drugs into the subcutaneous tissue.

Punch Biopsy
Punch biopsy removes a core of skin tissue for diagnostic purposes.

Liposuction
Liposuction is a surgical procedure to remove fat from subcutaneous tissue for cosmetic reasons.

Summary Table: Types of Skin Lesions
Lesion | Description | Color | Contents | Example |
|---|---|---|---|---|
Cyst | Elevated circular mound | Skin color or erythema | Semisolid or partly fluid filled | Acne sebaceous cyst |
Fissure | Small, cracklike crevice | Erythema | None, some fluid exudate | Dry, chapped skin |
Macule | Flat circle | Pigmented brown or black | None | Freckle, age spot |
Papule | Elevated | Skin color or erythema | Solid | Acne pimple |
Pustule | Elevated | White top | Pus | Acne whitehead |
Scale | Flat to slightly elevated, thin flake | White | None | Dandruff, psoriasis |
Vesicle | Elevated with pointed top | Erythema with transparent top | Clear fluid | Herpes, chickenpox, shingles |
Wheal | Elevated with broad, flat top | Erythema with pale top | Clear fluid | Insect bites, urticaria |
Key Medical Terminology
Dermatology: Study of the skin
Integumentary: Pertaining to the skin
Cutaneous: Pertaining to the skin
Melanocyte: Black pigment cell
Piloerection: Action of hair standing up
Subcutaneous: Beneath the skin
Formulas and Equations
Rule of Nines for Burn Assessment
The Rule of Nines is used to estimate the percentage of body surface area affected by burns:
Head: 9%
Chest: 9%
Abdomen: 9%
Each arm: 9%
Genitals: 1%
Each leg: 18%
Back: 18%
Conclusion
The integumentary system is essential for protection, sensation, thermoregulation, and homeostasis. Understanding its anatomy, physiology, and common diseases is fundamental for medical terminology students and healthcare professionals.