Human Anatomy & Physiology Laboratory Manual, Main Version, Global Edition, 12th edition

Published by Pearson (September 14, 2022) © 2023

  • Elaine N. Marieb
  • Lori A. Smith American River College



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For the two-semester A&P laboratory course.

Help manage time and improve learning inside and outside of the lab

The #1 best-selling Human Anatomy & Physiology Laboratory Manual helps students and instructors manage time inside and outside of the A&P lab classroom and works hand-in-hand with Pearson Mastering A&P, the leading online homework and learning program for A&P. The 12th Edition features dozens of new, full-color figures and photos in the review sheets, as well as revamped clinical application questions and critical thinking questions that reinforce the most important concepts from lab.

Continuing to set the standard for the 2-semester A&P laboratory course, the lab manual complies with the illustration and presentation style of the best-selling Marieb/Hoehn Human Anatomy & Physiology text but can accompany any A&P textbook. Options include three conventional versions: Main (12th Edition), Cat(13th Edition), and Fetal Pig (13th Edition).

Hallmark features of this title

  • The variety of laboratory exercises and activities offer organ dissections for rat, cow, and sheep specimens, plus full body dissections in the Cat and Pig versions.
  • Icons alert students to dissection activities, safety precautions, homeostatic imbalance sections, exercises with BIOPAC® equipment, and PhysioEx™ Exercises.
  • Workbook-Style design presents information in visual summary tables and streamlines background information, providing space to write and draw.
  • Group Challenge activities create an active learning environment.
  • Surface anatomy exercise features superb photos of muscle definition and clear surface landmarks for skeletal, muscular, and vascular structures.
  • Terminology reflects information in Terminologia Anatomica and Terminologia Histologica.

New and updated features of this title

  • Dozens of full-color figures and photos replace black and white line drawings in the Exercise Review Sheets.
  • Clinical Application Questions in the Exercise Review Sheets challenge students to apply lab concepts and critical thinking skills to realworld clinical scenarios. These streamlined questions are adapted from several of the “Why This Matters,” discussions in the previous edition.
  • UPDATED: BIOPAC procedures are included in the manual for 8 lab exercises and have been updated for the BIOPAC 4.0 software upgrade.


  • Exercise 1. The Language of Anatomy
  • Exercise 2. Organ Systems Overview

The Microscope and Its Uses

  • Exercise 3. The Microscope

The Cell

  • Exercise 4. The Cell: Anatomy and Division
  • Exercise 5. The Cell: Transport Mechanisms and Cell Permeability

Histology: Basic Tissues of the Body

  • Exercise 6. Classification of Tissues

The Integumentary System

  • Exercise 7. The Integumentary System

The Skeletal System

  • Exercise 8. Overview of the Skeleton: Classification and Structure of Bones and Cartilages Exercise 9. The Axial Skeleton
  • Exercise 10. The Appendicular Skeleton
  • Exercise 11. Articulations and Body Movements

The Muscular System

  • Exercise 12. Microscopic Anatomy and Organization of Skeletal Muscle
  • Exercise 13. Gross Anatomy of Muscular System
  • Exercise 14. Skeletal Muscle Physiology: Frogs and Human Subjects

The Nervous System

  • Exercise 15. Histology of Nervous Tissue
  • Exercise 16. Neurophysiology of Nerve Impulses: Frog Subjects
  • Exercise 17. Gross Anatomy of the Brain and Cranial Nerves
  • Exercise 18. Electroencephalography
  • Exercise 19. The Spinal Cord and Spinal Nerves
  • Exercise 20. The Autonomic Nervous System
  • Exercise 21. Human Reflex Physiology
  • Exercise 22. General Sensation
  • Exercise 23. Special Senses: Anatomy of the Visual System
  • Exercise 24. Special Senses: Visual Tests and Experiments
  • Exercise 25: Special Senses: Hearing and Equilibrium
  • Exercise 26. Special Senses: Olfaction and Taste

The Endocrine System

  • Exercise 27. Functional Anatomy of the Endocrine Glands
  • Exercise 28. Endocrine Wet Labs and Human Metabolism

The Circulatory System

  • Exercise 29. Blood
  • Exercise 30. Anatomy of the Heart
  • Exercise 31. Conduction System of the Heart and Electrocardiography
  • Exercise 32. Anatomy of Blood Vessels
  • Exercise 33. Human Cardiovascular Physiology: Blood Pressure and Pulse Determinations Exercise 34. Frog Cardiovascular Physiology
  • Exercise 35. The Lymphatic System and Immune Response

The Respiratory System

  • Exercise 36. Anatomy of the Respiratory System
  • Exercise 37. Respiratory System Physiology

The Digestive System

  • Exercise 38. Anatomy of the Digestive System
  • Exercise 39. Digestive System Processes: Chemical and Physical

The Urinary System

  • Exercise 40. Anatomy of the Urinary System
  • Exercise 41. Urinalysis

The Reproductive System, Development, and Heredity

  • Exercise 42. Anatomy of the Reproductive System
  • Exercise 43. Physiology of Reproduction: Gametogenesis and the Female Cycles
  • Exercise 44. Survey of Embryonic Development
  • Exercise 45. Principles of Heredity

Surface Anatomy

  • Exercise 46. Surface Anatomy Roundup

PhysioEx™ 9.1 Computer Simulations

  • Exercise 1. Cell Transport Mechanisms and Permeability
  • Exercise 2. Skeletal Muscle Physiology
  • Exercise 3. Neurophysiology of Nerve Impulses
  • Exercise 4. Endocrine System Physiology
  • Exercise 5. Cardiovascular Dynamics
  • Exercise 6. Cardiovascular Physiology
  • Exercise 7. Respiratory System Mechanics 
  • Exercise 8. Chemical and Physical Processes of Digestion
  • Exercise 9. Renal System Physiology
  • Exercise 10. Acid-Base Balance
  • Exercise 11. Blood Analysis
  • Exercise 12: Serological Testing

The CAT version of the lab manual will each have the following additional dissection exercises:

  • Cat Dissection Exercises
  • Exercise 1. Dissection and Identification of Cat Muscles
  • Exercise 2. Dissection of Cat Spinal Nerves
  • Exercise 3. Identification of Selected Endocrine Organs of the Cat
  • Exercise 4. Dissection of the Blood Vessels of the Cat
  • Exercise 5. The Main Lymphatic Ducts of the Cat
  • Exercise 6. Dissection of the Respiratory System of the Cat
  • Exercise 7. Dissection of the Digestive System of the Cat
  • Exercise 8. Dissection of the Urinary System of the Cat
  • Exercise 9. Dissection of the Reproductive System of the Cat

The PIG version of the lab manual will each have the following additional dissection exercises:

  • Pig Dissection Exercises
  • Exercise 1. Dissection and Identification of Fetal Pig Muscles
  • Exercise 2. Dissection of the Spinal Cord and Spinal Nerves of the Fetal Pig
  • Exercise 3. Identification of Selected Endocrine Organs of the Fetal Pig
  • Exercise 4. Dissection of Blood Vessels and Main Lymphatic Ducts of the Fetal Pig
  • Exercise 5. Dissection of the Respiratory System of the Fetal Pig
  • Exercise 6. Dissection of the Digestive System of the Fetal Pig
  • Exercise 7. Dissection of the Urinary System of the Fetal Pig
  • Exercise 8. Dissection of the Reproductive System of the Fetal Pig

Elaine N. Marieb

For Elaine N. Marieb, taking the student’s perspective into account has always been an integral part of her teaching style. Dr. Marieb began her teaching career at Springfield College, where she taught anatomy and physiology to physical education majors. She then joined the faculty of the Biological Science Division of Holyoke Community College in 1969 after receiving her Ph.D. in zoology from the University of Massachusetts at Amherst. While teaching at Holyoke Community College, where many of her students were pursuing nursing degrees, she developed a desire to better understand the relationship be-tween the scientific study of the human body and the clinical aspects of the nursing practice. To that end, while continuing to teach full time, Dr. Marieb pursued her nursing education, which culminated in a Master of Science degree with a clinical specialization in gerontology from the University of Massachusetts. It is this experience that has informed the development of the unique perspective and accessibility for which her publications are known.

Dr. Marieb has partnered with Benjamin Cummings for over 30 years. Her first work was Human Anatomy & Physiology Laboratory Manual (Cat Version), which came out in 1981. In the years since, several other lab manual versions and study guides, as well as the softcover Essentials of Human Anatomy & Physiology textbook, have hit the campus bookstores. This textbook, now in its 11th edition, made its appearance in 1989 and is the latest expression of her commitment to the needs of students studying human anatomy and physiology.

Dr. Marieb has given generously to colleges both near and far to provide opportunities for students to further their education. She contributes to the New Directions, New Careers Program at Holyoke Community College by funding a staffed drop-in center and by providing several full-tuition scholarships each year for women who are returning to college after a hiatus or attending college for the first time and who would be unable to continue their studies without financial support. She funds the E. N. Marieb Science Research Awards at Mount Holyoke College, which promotes research by undergraduate science majors, and has underwritten renovation and updating of one of the biology labs in Clapp Laboratory at that college. Dr. Marieb also contributes to the University of Massachusetts at Amherst where she generously provided funding for recon-struction and instrumentation of a cutting-edge cytology re-search laboratory. Recognizing the severe national shortage of nursing faculty, she underwrites the Nursing Scholars of the Future Grant Program at the university.

In 1994, Dr. Marieb received the Benefactor Award from the National Council for Resource Development, American Association of Community Colleges, which recognizes her ongoing sponsorship of student scholarships, faculty teaching awards, and other academic contributions to Holyoke Community College. In May 2000, the science building at Holyoke Community College was named in her honor.

Marieb is an active member of the Human Anatomy and Physiology Society (HAPS) and the American Association for the Advancement of Science (AAAS). Additionally, while actively engaged as an author, Dr. Marieb serves as a consultant for the Benjamin Cummings Interactive Physiology® series.

When not involved in academic pursuits, Dr. Marieb is a world traveler and has vowed to visit every country on this planet. Shorter term, she serves on the scholarship committee of the Women’s Resources Center and on the board of directors of several charitable institutions in Sarasota County. She is an enthusiastic supporter of the local arts and enjoys a competitive match of doubles tennis.

Lori A. Smith received her Ph.D. in Biochemistry from the University of California at Davis. Before discovering her passion for teaching, she worked as a research scientist and project leader in the medical diagnostics industry. In 1999, she joined the faculty at American River College in the Biology Department. Currently she teaches anatomy and physiology and microbiology to pre-nursing and mortuary science students at American River College. Starting in 2005, she began co-authoring Pearson’s PhysioEx: Laboratory Simulations in Physiology and has continued to co-author several versions of the software and lab manual. Dr. Smith has been awarded “Instructor of the Year” by the American River College Associated Students for her commitment to serving students, and she is a member of the Human Anatomy and Physiology Society (HAPS) and the National Association of Biology Teachers (NABT).

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