Question 1

Which process ensures that B cells do not recognize self-antigens and prevents autoimmunity during their maturation in the bone marrow?

Accepted Answer

Destruction of self-reactive B cells

Question 2

A patient receives an injection of preformed antibodies against tetanus toxin. Which type of immunity is this an example of?

Accepted Answer

Passive immunity, artificially acquired

Question 3

Which antibody class is most prevalent in the body and is the only one able to cross the placenta to provide immunity to a developing fetus?

Accepted Answer

IgG

Question 4

During the secondary immune response, which antibody class is produced in the greatest quantity and binds antigens with higher affinity?

Accepted Answer

IgG

Question 5

Which antibody class is most effective at agglutination and precipitation due to its structure as a pentamer with 10 antigen-binding sites?

Accepted Answer

IgM

Question 6

A child develops immunity to measles after recovering from the infection. Which type of immunity is this?

Accepted Answer

Active immunity, naturally acquired

Question 7

Which region of the antibody molecule is responsible for antigen recognition and binding?

Accepted Answer

Variable region

Question 8

What is the primary function of IgE antibodies in the body?

Accepted Answer

Triggering inflammation and allergic reactions

Question 9

Which process describes the ability of a B cell clone to switch from producing IgM to IgG antibodies while maintaining the same antigen specificity?

Accepted Answer

Class switching

Question 10

A patient exposed to hepatitis B virus receives a vaccine containing inactivated viral proteins. What is the expected immune response?

Accepted Answer

Primary immune response with memory cell formation

Question 11

Which antibody class is found in secretions such as saliva, tears, and breast milk, and is usually a dimer?

Accepted Answer

IgA

Question 12

What is the main difference between the primary and secondary immune responses?

Accepted Answer

Secondary response produces more antibodies with higher affinity and a shorter lag phase

Question 13

Which function of antibodies involves coating pathogens to enhance their uptake and destruction by phagocytes?

Accepted Answer

Opsonization

Question 14

A newborn receives IgG antibodies from its mother through the placenta. How long will this passive immunity typically last?

Accepted Answer

About three months

Question 15

Which antibody class acts as an antigen receptor on the surface of B cells and is not secreted in significant amounts?

Accepted Answer

IgD

Question 16

If a person is exposed to a toxin and receives an injection of antibodies against that toxin, which of the following is true?

Accepted Answer

The person will have temporary protection as long as the antibodies remain in the bloodstream

Question 17

Which of the following best describes the structure of an antibody monomer?

Accepted Answer

Four peptide chains: two heavy and two light, forming a Y-shaped molecule

Question 18

What is the effect of antibody-mediated agglutination on pathogens?

Accepted Answer

It makes it easier for phagocytes to ingest the complex

Question 19

Which antibody class is primarily responsible for allergic reactions by binding to mast cells and triggering the release of histamine?

Accepted Answer

IgE

Question 20

A person receives a vaccine containing a toxoid. What is the expected outcome?

Accepted Answer

Production of antibodies against the toxin

Adaptive Immunity: Antibody-Mediated Immunity (ANP College Study Notes)

Study Guide - Practice Questions