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Chapter 16: The Endocrine System – Human Anatomy & Physiology Study Notes

Study Guide - Smart Notes

Tailored notes based on your materials, expanded with key definitions, examples, and context.

Endocrine System Overview

Introduction to the Endocrine System

The endocrine system is one of the two major control systems of the body, working alongside the nervous system to maintain homeostasis. It influences metabolic activities through hormones transported in the blood, producing responses that are slower but longer-lasting than those of the nervous system.

  • Endocrinology: The study of hormones and endocrine organs.

  • Main functions:

    • Reproduction

    • Growth and development

    • Maintenance of electrolyte, water, and nutrient balance of blood

    • Regulation of cellular metabolism and energy balance

    • Mobilization of body defenses

Comparison of Nervous and Endocrine Systems

Functional Differences

The nervous and endocrine systems both regulate body functions, but they differ in their mechanisms and effects.

Nervous System

Endocrine System

Initiates responses rapidly

Initiates responses slowly

Short-duration responses

Long-duration responses

Acts via action potentials and neurotransmitters

Acts via hormones released into the blood

Acts at specific locations determined by axon pathways

Acts at diffuse locations—targets can be anywhere blood reaches

Neurotransmitters act over short distances

Hormones act over long distances

Signal strength coded by frequency of action potentials

Signal strength coded by concentration of hormone

Major Topics in the Endocrine System

Chapter Structure

This chapter covers the following key areas of the endocrine system:

  • 16.1: The endocrine system as a major control system

  • 16.2: Hormone structure

  • 16.3: Mechanisms of hormone action

  • 16.4: Stimuli causing hormone release

  • 16.5: Determinants of cell responses to hormones

  • 16.6: The hypothalamus and its control of the pituitary gland

  • 16.7: The thyroid gland

  • 16.8: The parathyroid glands

  • 16.9: The adrenal glands

  • 16.10: The pineal gland

  • 16.11: Organs with other major functions that also secrete hormones

  • Developmental Aspects: Environmental effects and changes throughout life

Key Terms and Concepts

  • Hormone: A chemical messenger secreted by endocrine glands, transported by blood to target organs.

  • Endocrine gland: Ductless gland that releases hormones directly into the bloodstream.

  • Homeostasis: The maintenance of a stable internal environment.

  • Target cell: A cell that has receptors for a specific hormone.

Example: Hormonal Regulation of Growth

Growth hormone (GH) is secreted by the anterior pituitary gland and stimulates growth and metabolism in target tissues. Its release is regulated by hypothalamic hormones and feedback mechanisms.

  • GH stimulates:

    • Cellular uptake of nutrients

    • Protein synthesis

    • Bone and muscle growth

Summary Table: Endocrine System Functions

Function

Example Hormone

Target Tissue

Growth and development

Growth hormone (GH)

Bone, muscle

Metabolism regulation

Thyroid hormone (TH)

Most body cells

Electrolyte balance

Aldosterone

Kidneys

Stress response

Cortisol

Various tissues

Additional info: These notes are based on the introductory slides and chapter outline for "Chapter 16: The Endocrine System" from Marieb Human Anatomy & Physiology. For detailed mechanisms, hormone pathways, and clinical correlations, refer to the full chapter content.

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