Question 1

Which of the following is NOT a function of the integumentary system?

Accepted Answer

Production of red blood cells

Question 2

A patient presents with a bluish tint to their lips and nail beds. Which condition is most likely indicated?

Accepted Answer

Cyanosis

Question 3

Which layer of the epidermis is only found in thick skin, such as the palms and soles?

Accepted Answer

Stratum lucidum

Question 4

Which cell type in the epidermis is responsible for producing melanin?

Accepted Answer

Melanocyte

Question 5

A surgeon is planning an incision on the trunk. To minimize scarring, the incision should be made:

Accepted Answer

Parallel to tension (cleavage) lines

Question 6

Which gland is primarily responsible for thermoregulation through the secretion of a watery fluid?

Accepted Answer

Eccrine sweat gland

Question 7

Which of the following best describes the process by which the skin helps regulate body temperature when it is too hot?

Accepted Answer

Dilation of dermal blood vessels and increased sweat production

Question 8

Which of the following is TRUE regarding the stratum basale?

Accepted Answer

It contains mitotically active stem cells

Question 9

A patient with albinism is at increased risk for which of the following?

Accepted Answer

Keratinocyte DNA damage from UV radiation

Question 10

Which of the following best explains why individuals with darker skin living near the equator have an evolutionary advantage?

Accepted Answer

They prevent excess vitamin D production, avoiding hypercalcemia

Question 11

Which of the following is a correct pairing of a skin marking and its significance?

Accepted Answer

Tension lines – indicate the direction of collagen bundles in the dermis

Question 12

Which of the following best describes the secretion method of sebaceous glands?

Accepted Answer

Holocrine secretion

Question 13

A patient presents with a scaly plaque on the scalp that bleeds and does not heal. Biopsy reveals abnormal keratinocytes in the stratum spinosum. What is the most likely diagnosis?

Accepted Answer

Squamous cell carcinoma

Question 14

Which of the following is TRUE regarding the hypodermis?

Accepted Answer

It is composed primarily of loose connective and adipose tissue

Question 15

Which of the following best describes the role of dendritic (Langerhans) cells in the epidermis?

Accepted Answer

They act as phagocytes to protect against pathogens

Question 16

Which of the following is a distinguishing feature of apocrine sweat glands compared to eccrine sweat glands?

Accepted Answer

They secrete a protein-rich fluid into hair follicles

Question 17

Which of the following best describes the process of vitamin D synthesis in the skin?

Accepted Answer

UV radiation converts a precursor in the epidermis to cholecalciferol, which is then modified by the liver and kidneys to form calcitriol

Question 18

Which of the following best explains why calluses form on the hands of a manual laborer?

Accepted Answer

Increased mitosis in the stratum basale leads to a thicker stratum corneum

Question 19

Which of the following is TRUE regarding the growth of hair and nails?

Accepted Answer

Both grow from actively dividing cells in the matrix region

Question 20

A patient presents with yellowing of the skin and sclera. Which pigment is most likely responsible for this appearance?

Accepted Answer

Bilirubin

The Integumentary System: Structure, Function, and Clinical Relevance

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