Which statement best describes the difference between Michaelis-Menten and allosteric enzymes in negative feedback regulation?

• A. Michaelis-Menten enzymes are regulated by substrate concentration, while allosteric enzymes are regulated by product concentration.
• B. Allosteric enzymes are always more efficient than Michaelis-Menten enzymes.
• C. Allosteric enzymes bind substrates at the active site only.
• D. Michaelis-Menten enzymes are not involved in feedback regulation.

Answer: (A)