An enzyme is inhibited by an uncompetitive inhibitor. If the original Km is 5 mM and Vmax is 100 μmol/min, what happens to the apparent Km and Vmax?

• A. Apparent Km increases, and apparent Vmax decreases.
• B. Apparent Km remains unchanged, and apparent Vmax increases.
• C. Apparent Km decreases, and apparent Vmax decreases.
• D. Apparent Km increases, and apparent Vmax remains unchanged.

Answer: (C)