During intense physical activity, how does hemoglobin carbonation facilitate oxygen delivery to active muscles?

• A. Hemoglobin carbonation destabilizes the T state, preventing oxygen release due to high CO2 levels in active muscles.
• B. Hemoglobin carbonation stabilizes the T state, enhancing oxygen release due to high CO2 levels in active muscles.
• C. Hemoglobin carbonation has no effect on oxygen delivery to active muscles.
• D. Hemoglobin carbonation stabilizes the R state, enhancing oxygen binding due to high CO2 levels in active muscles.

Answer: (B)