How do noncompetitive inhibitors bind to enzymes compared to mixed inhibitors?

• A. Noncompetitive inhibitors bind with different affinities to the free enzyme and the enzyme-substrate complex.
• B. Noncompetitive inhibitors only bind to the enzyme-substrate complex.
• C. Noncompetitive inhibitors bind with the same affinity to both the free enzyme and the enzyme-substrate complex.
• D. Noncompetitive inhibitors only bind to the free enzyme.

Answer: (C)