Which of the following statements best describes noncompetitive inhibition?

• A. Noncompetitive inhibitors are a type of competitive inhibitor.
• B. Noncompetitive inhibitors bind to an allosteric site, reducing enzyme activity without affecting substrate binding.
• C. Noncompetitive inhibitors increase the Km of the enzyme-catalyzed reaction.
• D. Noncompetitive inhibitors bind to the active site of the enzyme, preventing substrate binding.

Answer: (B)