What is the role of hexokinase, phosphofructokinase, and pyruvate kinase in glycolysis?

• A. They are responsible for the transport of glucose into the cell.
• B. They catalyze reversible reactions that regulate glycolysis.
• C. They are involved in the synthesis of glucose from pyruvate.
• D. They catalyze irreversible reactions that drive glycolysis forward due to their negative delta G values.

Answer: (D)