Given a protein with a mix of hydrophobic and hydrophilic amino acids, predict the likely distribution of these amino acids in the folded protein structure.

• A. The distribution is random and cannot be predicted.
• B. Both hydrophobic and hydrophilic amino acids will be evenly distributed throughout the protein.
• C. Hydrophobic amino acids will be in the interior, while hydrophilic amino acids will be on the exterior.
• D. Hydrophobic amino acids will be on the exterior, while hydrophilic amino acids will be in the interior.

Answer: (C)