DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel. This will provide the basis for

• A. Leading and lagging strands of DNA
• B. Formation of Okazaki fragments
• C. Origin of replication
• D. Both leading and lagging strand and Okazaki fragments
• E. DNA Ligase and single-stranded binding proteins

Answer: (D)