BackBiology 111 Exam 3 Study Guide: Cellular Respiration, Mitosis & Meiosis, Inheritance, and DNA Structure
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Q1. What kind of energy change is associated with the citric acid cycle? (Is it endergonic or exergonic?)
Background
Topic: Cellular Respiration – Citric Acid Cycle (Krebs Cycle)
This question tests your understanding of the energy transformations that occur during the citric acid cycle, a key metabolic pathway in cellular respiration.
Key Terms
Endergonic: A reaction that requires energy input.
Exergonic: A reaction that releases energy.
Citric Acid Cycle: Also known as the Krebs cycle; a series of chemical reactions used by all aerobic organisms to generate energy.
Step-by-Step Guidance
Recall that the citric acid cycle is part of cellular respiration, which is the process cells use to extract energy from nutrients.
Think about whether the cycle as a whole releases energy or requires energy input. Consider what happens to the high-energy electrons and the production of ATP, NADH, and FADH2.
Remember that the products of the cycle are used to generate more ATP in the electron transport chain, indicating the direction of energy flow.
Try solving on your own before revealing the answer!
Q2. Know the stages of Respiration: Glycolysis, Pyruvate oxidation, Krebs Cycle, and the ETC. Know what is added to the cycle (ATP, NAD+, etc.) and what comes out.
Background
Topic: Cellular Respiration Pathways
This question tests your ability to identify the main stages of cellular respiration and the key inputs and outputs of each stage.
Key Terms
Glycolysis: The breakdown of glucose into pyruvate.
Pyruvate Oxidation: Conversion of pyruvate to acetyl-CoA.
Krebs Cycle (Citric Acid Cycle): Series of reactions generating NADH, FADH2, and ATP.
Electron Transport Chain (ETC): Uses electrons from NADH and FADH2 to produce ATP.
Step-by-Step Guidance
List the four main stages of cellular respiration in order: Glycolysis, Pyruvate Oxidation, Krebs Cycle, and Electron Transport Chain.
For each stage, identify the main reactants (what goes in) and products (what comes out). For example, glycolysis uses glucose and produces pyruvate, ATP, and NADH.
Consider the role of electron carriers (NAD+, FAD) and ATP in each stage.
Think about where each stage occurs in the cell (cytoplasm or mitochondria).
Try solving on your own before revealing the answer!
Q3. Be able to label the diagram of the cycle with the reactants and products.
Background
Topic: Cellular Respiration – Krebs Cycle Diagram
This question tests your ability to visually identify and label the key molecules involved in the Krebs cycle.
Key Terms
Reactants: Molecules that enter a reaction (e.g., Acetyl-CoA, NAD+).
Products: Molecules produced (e.g., CO2, NADH, FADH2, ATP).
Step-by-Step Guidance
Review a diagram of the Krebs cycle and identify the entry point (Acetyl-CoA).
Label where NAD+, FAD, and GDP/ADP are used, and where NADH, FADH2, GTP/ATP, and CO2 are produced.
Note the cyclical nature of the pathway and how oxaloacetate is regenerated.
Try solving on your own before revealing the answer!
Q4. Where does each stage of cellular respiration happen?
Background
Topic: Cellular Respiration – Cellular Compartments
This question tests your knowledge of cell structure and the localization of metabolic pathways.
Key Terms
Cytoplasm: Fluid inside the cell where glycolysis occurs.
Mitochondria: Organelle where pyruvate oxidation, Krebs cycle, and ETC occur.
Step-by-Step Guidance
List each stage of cellular respiration: Glycolysis, Pyruvate Oxidation, Krebs Cycle, Electron Transport Chain.
Recall the specific location for each stage (e.g., cytoplasm, mitochondrial matrix, inner mitochondrial membrane).
Think about why compartmentalization is important for these processes.
Try solving on your own before revealing the answer!
Q5. Why is it important that the electrons are passed down the electron transport chain?
Background
Topic: Cellular Respiration – Electron Transport Chain (ETC)
This question tests your understanding of how the ETC generates ATP and why electron transfer is crucial.
Key Terms
Electron Transport Chain: Series of protein complexes that transfer electrons and pump protons.
ATP Synthesis: The process of making ATP using the energy from a proton gradient.
Step-by-Step Guidance
Recall that electrons from NADH and FADH2 are transferred through the ETC.
Consider how this electron flow is coupled to proton pumping across the inner mitochondrial membrane.
Think about how the resulting proton gradient is used to drive ATP synthesis via ATP synthase.
Try solving on your own before revealing the answer!
Q6. Why does your respiration rate increase when you are exercising (explain in context of the citric acid cycle)?
Background
Topic: Cellular Respiration and Exercise Physiology
This question tests your understanding of metabolic demand and the role of the citric acid cycle during increased activity.
Key Terms
Respiration Rate: The number of breaths per minute.
ATP Demand: The need for more energy during exercise.
Citric Acid Cycle: Central pathway for energy production.
Step-by-Step Guidance
Consider how muscle activity increases the demand for ATP.
Think about how the citric acid cycle responds to increased substrate (acetyl-CoA) and oxygen availability.
Relate increased respiration rate to the need for more oxygen to support the citric acid cycle and ETC.
Try solving on your own before revealing the answer!
Q7. What is an electron acceptor and why does it accept an electron? What does the electron acceptor do with the electron?
Background
Topic: Redox Reactions in Cellular Respiration
This question tests your understanding of electron carriers and their role in energy transfer.
Key Terms
Electron Acceptor: A molecule that gains electrons during a redox reaction.
Redox Reaction: Chemical reaction involving the transfer of electrons.
Step-by-Step Guidance
Define what an electron acceptor is in the context of cellular respiration (e.g., NAD+, FAD, O2).
Explain why electron acceptors are necessary for the flow of electrons and energy extraction.
Describe what happens to the electron after it is accepted (e.g., used to form water, generate ATP).
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Q8. What is oxygen used for during cellular respiration? Why do you need oxygen to live?
Background
Topic: Role of Oxygen in Cellular Respiration
This question tests your understanding of oxygen's role as the final electron acceptor in the electron transport chain.
Key Terms
Final Electron Acceptor: The molecule that receives electrons at the end of the ETC (oxygen in aerobic respiration).
Water Formation: Oxygen combines with electrons and protons to form water.
Step-by-Step Guidance
Recall that oxygen is required at the end of the electron transport chain.
Explain what happens if oxygen is not present (e.g., backup of electrons, halt in ATP production).
Describe why this process is essential for life in aerobic organisms.
Try solving on your own before revealing the answer!
Q9. What does one glucose molecule make throughout the Citric Acid cycle (hint: the cycle runs 2x for each glucose)?
Background
Topic: Citric Acid Cycle Yield per Glucose
This question tests your ability to calculate the total products generated from one glucose molecule during the citric acid cycle.
Key Terms
Glucose: A six-carbon sugar that is split into two pyruvate molecules.
Citric Acid Cycle: Each glucose yields two turns of the cycle.
Step-by-Step Guidance
Recall that one glucose produces two pyruvate molecules, each entering the citric acid cycle.
List the products generated per turn of the cycle (e.g., NADH, FADH2, ATP/GTP, CO2).
Multiply the per-cycle yield by two to get the total per glucose molecule.
Try solving on your own before revealing the answer!
Q10. Anaerobic and aerobic respiration: how do they differ? What are the differences between fermentation and the lactic acid cycle?
Background
Topic: Types of Respiration and Fermentation
This question tests your understanding of the differences between aerobic and anaerobic pathways, and between fermentation types.
Key Terms
Aerobic Respiration: Uses oxygen as the final electron acceptor.
Anaerobic Respiration: Does not use oxygen; uses other molecules as electron acceptors.
Fermentation: Process that allows glycolysis to continue in the absence of oxygen.
Lactic Acid Cycle: Produces lactic acid as a byproduct.
Step-by-Step Guidance
Define aerobic and anaerobic respiration and identify their key differences (e.g., oxygen use, ATP yield).
Explain what fermentation is and how it differs from the lactic acid cycle.
List the products of each process and their significance for the cell.
Try solving on your own before revealing the answer!
Q11. What is the function of cellular respiration? Write out the basic formula and list why each reactant is necessary.
Background
Topic: Cellular Respiration Overview
This question tests your understanding of the overall purpose of cellular respiration and the chemical equation involved.
Key Formula
Key Terms
Glucose (C6H12O6): Main fuel molecule.
Oxygen (O2): Final electron acceptor.
ATP: Main energy currency of the cell.
Step-by-Step Guidance
Write out the overall equation for cellular respiration.
Identify each reactant and product in the equation.
Explain the role of each reactant (e.g., glucose as energy source, oxygen for electron acceptance).