Question 1

Which combination of antigens and antibodies is found in a person with blood type B?

Accepted Answer

B antigen on red blood cells, anti-A antibodies in plasma

Question 2

A child is born to parents who both have blood type AB. What are the possible blood types (phenotypes) of their child?

Accepted Answer

Only AB

Question 3

If a person with blood type O receives a transfusion of type A blood, what is the most likely outcome?

Accepted Answer

Agglutination and possible hemolysis due to anti-A antibodies attacking A antigens

Question 4

Which genotype(s) correspond to Rh-positive blood type?

Accepted Answer

$RR$ or $Rr$

Question 5

A mother is Rh-negative ($rr$) and her baby is Rh-positive ($Rr$). What complication can arise if their blood mixes during birth?

Accepted Answer

The mother may develop antibodies against Rh antigen, risking hemolytic disease in future Rh-positive pregnancies

Question 6

Which blood type is considered the universal donor and why?

Accepted Answer

Type O, because it lacks A and B antigens

Question 7

What is the genotype of a person with blood type O?

Accepted Answer

$ii$

Question 8

If a person has anti-A and anti-B antibodies in their plasma, what is their blood type?

Accepted Answer

Type O

Question 9

During a blood typing experiment, agglutination occurs when anti-B serum is added to a blood sample. What does this indicate?

Accepted Answer

The blood sample contains B antigens

Question 10

A couple, both with genotype $I^A i$, have a child. What is the probability that their child will have blood type O?

Accepted Answer

$25\%$

Question 11

Why is it important to match both ABO and Rh blood types during transfusions?

Accepted Answer

To prevent agglutination and hemolysis caused by antibody-antigen reactions

Question 12

Which of the following best explains agglutination in blood typing?

Accepted Answer

Antibodies in plasma bind to matching antigens on red blood cells, causing clumping

Question 13

A person with genotype $I^A I^B$ will have which blood type and what antibodies in their plasma?

Accepted Answer

Type AB, no antibodies

Question 14

If a father is Rh-positive ($Rr$) and the mother is Rh-negative ($rr$), what is the probability that their child will be Rh-negative?

Accepted Answer

$50\%$

Question 15

Which blood type is considered the universal recipient and why?

Accepted Answer

Type AB, because it has no antibodies

Question 16

A woman with blood type O and Rh-negative ($ii, rr$) marries a man with blood type AB and Rh-positive ($I^A I^B, Rr$). What is the probability that their child will have blood type B and be Rh-negative?

Accepted Answer

$25\%$

Question 17

Which statement about the Rh factor is correct?

Accepted Answer

Rh-negative individuals can develop antibodies against Rh antigen after exposure

Question 18

What is the main risk for an Rh-negative mother during her second pregnancy with an Rh-positive baby?

Accepted Answer

Her antibodies may attack the baby's red blood cells, causing hemolytic disease of the newborn

Question 19

Which of the following is NOT a possible genotype for a person with blood type A?

Accepted Answer

$ii$

Question 20

In a blood typing experiment, why is it important to use a clean toothpick for each sample?

Accepted Answer

To prevent cross-contamination and inaccurate agglutination results

Blood Typing and Applied Human Genetics: Study Notes

Study Guide - Practice Questions

Study Guide - Flashcards