Q: If a cell sample contains 20 cells in mitosis and 80 total cells observed, what is the mitotic index?

$$ \frac{20}{80} \times 100 = 25\% $$

Question 1

Which of the following best describes a chromatid?

Accepted Answer

One of the two identical strands of DNA visible during mitosis.

Question 2

During which stage of mitosis do chromosomes align at the metaphase plate?

Accepted Answer

Metaphase

Question 3

What is the main function of spindle fibers during mitosis?

Accepted Answer

They pull chromosomes apart during mitosis.

Question 4

Which of the following is a property of cancer cells?

Accepted Answer

They have uncontrolled division.

Question 5

If a cell sample contains 20 cells in mitosis and 80 total cells observed, what is the mitotic index?

Accepted Answer

$$ \frac{20}{80} 	imes 100 = 25\% $$

Question 6

Which checkpoint is most likely to prevent a cell with damaged DNA from entering mitosis?

Accepted Answer

G1/S checkpoint

Question 7

What is the correct sequence of mitosis stages?

Accepted Answer

Prophase, Metaphase, Anaphase, Telophase

Question 8

A mutation in the p53 gene would most likely result in which of the following?

Accepted Answer

Uncontrolled cell division due to failure to stop damaged cells.

Question 9

Which structure is responsible for holding sister chromatids together?

Accepted Answer

Centromere

Question 10

During which phase of the cell cycle does DNA replication occur?

Accepted Answer

S phase of Interphase

Question 11

Which of the following best describes cytokinesis?

Accepted Answer

Division of the cytoplasm into 2 daughter cells

Question 12

If a tissue sample has a mitotic index of $$ 12.5\% $$, what does this indicate about the tissue?

Accepted Answer

12.5% of the cells are currently undergoing mitosis.

Question 13

Which event occurs during anaphase of mitosis?

Accepted Answer

Sister chromatids separate and move to opposite poles.

Question 14

A scientist observes that a cell has condensed chromosomes, a disintegrating nuclear membrane, and spindle fibers forming. Which stage is this cell in?

Accepted Answer

Prophase

Question 15

Which of the following is NOT a characteristic of cancer cells?

Accepted Answer

Contact inhibition

Question 16

If a cell fails to attach its chromosomes to spindle fibers during metaphase, what is the most likely consequence?

Accepted Answer

The cell cycle will halt at the metaphase checkpoint.

Question 17

Which of the following best explains why the mitotic index is often higher in cancerous tissue compared to normal tissue?

Accepted Answer

Cancer cells divide more rapidly, increasing the proportion of cells in mitosis.

Question 18

Which of the following transitions is correct during the cell cycle?

Accepted Answer

Chromatin → Chromosome → Chromatid

Question 19

Which process ensures that each daughter cell receives an identical set of chromosomes?

Accepted Answer

Mitosis

Question 20

A researcher finds that a tissue sample has a high mitotic index and cells with abnormal nuclei. What is the most likely explanation?

Accepted Answer

The tissue is likely cancerous due to uncontrolled cell division.

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