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Molecular Biology: Nucleic Acids, Gene Expression, and Regulation

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Organization of DNA in the Cell

  • DNA Replication
    05:46
  • Organization of DNA in the Cell
    06:52

Introduction to DNA Replication

  • Unwinding the DNA: Topoisomerase, Helicase & SSBs
    05:10
  • Components of DNA Replication
    04:47
  • Origin of Replication
    03:33

Leading & Lagging DNA Strands

  • Leading & Lagging DNA Strands
    05:15

Telomeres

  • Telomeres
    04:25

DNA Repair

  • DNA Repair
    03:20
  • DNA Proofreading & Repair Enzymes
    02:12

Central Dogma

  • Central Dogma
    05:45

Genetic Code

  • How to Use the Genetic Code
    11:39
  • Genetic Code
    01:28

Mutations

  • Mutations
    02:29
  • Types of Mutations
    08:44

Introduction to Transcription

  • Overview of Transcription
    07:44
  • Introduction to Transcription
    05:51

Steps of Transcription

  • 3) Termination of Transcription
    02:44
  • 1) Initiation of Transcription
    04:16
  • 2) Elongation of Transcription
    04:01

Eukaryotic RNA Processing and Splicing

  • Eukaryotic RNA Processing and Splicing
    02:32
  • 2) RNA Splicing Creates Mature mRNA
    08:44
  • 1) RNA Processing
    04:19

Introduction to Translation

  • Ribosomal tRNA Binding Sites
    06:16
  • Ribosome Subunits
    08:42
  • Introduction to Translation
    06:12

Steps of Translation

  • 2) Elongation of Translation
    04:59
  • 3) Termination of Translation
    02:16
  • 1) Initiation of Translation
    05:03

Post-Translational Modification

  • Post-Translational Modification
    04:26

Introduction to Regulation of Gene Expression

  • Positive vs Negative Gene Regulation
    02:17
  • Introduction to Regulation of Gene Expression
    06:40

Prokaryotic Gene Regulation via Operons

  • Inducible Operons
    04:25
  • Prokaryotic Gene Regulation via Operons
    00:53
  • Repressible Operons
    03:42

The Lac Operon

  • In the Absence of Lactose
    04:34
  • The Lac Operon
    07:06
  • In the Presence of Lactose
    03:56

The Trp Operon

  • In the Presence of Tryptophan
    03:11
  • The Trp Operon
    05:30
  • In the Absence of Tryptophan
    03:42

Review of the Lac Operon & Trp Operon

  • Review of the Lac Operon & Trp Operon
    06:24

Eukaryotic Chromatin Modifications

  • Eukaryotic Chromatin Modifications
    03:55
  • Histone Acetylation
    04:14
  • DNA Methylation
    03:39

Eukaryotic Transcriptional Control

  • Introduction to Transcription Factors
    03:32
  • General Transcription Factors
    03:51
  • Specific Transcription Factors
    03:57

Eukaryotic Post-Transcriptional Regulation

  • Eukaryotic Post-Transcriptional Regulation
    01:56
  • 3) RNA Interference
    04:16
  • 1) Alternative RNA Splicing
    05:17

Eukaryotic Post-Translational Regulation

  • Protein Ubiquitination
    02:45
  • Eukaryotic Post-Translational Regulation
    03:55

Cancer

  • Types of Genes Regulating Cell Growth
    04:02
  • Cancer
    03:22