BackTumor Viruses definitions
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1/15BackSkip to main contentBackOncogenic Viruses
Agents capable of initiating cancer by altering host cell genetic material or producing proteins that disrupt normal cellular regulation. Viral Genome Integration
Process where foreign genetic material becomes part of host DNA, potentially disrupting key genes and promoting malignancy. RAS
A GTPase frequently mutated in cancers, whose function can be compromised by insertion of foreign genetic material. Tumor Suppressor
Cellular component that prevents uncontrolled growth; its inhibition or destruction increases cancer risk. Cell Cycle Control
Regulatory system ensuring orderly cell division; disruption can favor unchecked proliferation. Apoptosis
Programmed cell death mechanism; its reduction allows abnormal cells to survive and multiply. DNA Replication
Cellular process hijacked by viruses to duplicate their own genetic material within host cells. Hepatitis B
Virus linked to liver cancer, known for its ability to alter host cell functions and promote malignancy. Hepatitis C
Pathogen associated with liver cancer, contributing to oncogenesis through chronic infection. Human Papillomavirus
Virus implicated in cervical, head, neck, and throat cancers, expressing proteins that disrupt tumor suppression. E6
Protein that binds and leads to the destruction of a key tumor suppressor, facilitating cancer development. E7
Protein that inhibits the function of the retinoblastoma tumor suppressor, increasing cancer susceptibility. Retinoblastoma Tumor Suppressor
Cellular regulator of proliferation, whose inhibition by viral proteins raises the likelihood of tumor formation. Kaposi Sarcoma
Cancer often seen in immunocompromised individuals, associated with herpes virus infection. AIDS
Immunodeficiency condition that increases vulnerability to oncogenic viral infections and related cancers.
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