$\text{Cytoplasmic Volume} \div \text{Genome Size} \geq \text{Critical Ratio}$

Question 1

Which of the following best describes the process by which bacteria reproduce?

Accepted Answer

Binary fission

Question 2

During which phase of the cell cycle does DNA replication occur?

Accepted Answer

S phase

Question 3

A human somatic cell contains 46 chromosomes. How many chromosomes will a human gamete contain?

Accepted Answer

23

Question 4

Which structure is responsible for organizing microtubules during mitosis in animal cells?

Accepted Answer

Centrosome

Question 5

What is the main function of the G1 checkpoint in the cell cycle?

Accepted Answer

To determine if the cell will proceed to division or enter G0

Question 6

Which of the following equations correctly represents the diploid and haploid chromosome numbers in humans?

Accepted Answer

$2n = 46$, $n = 23$

Question 7

Which phase of mitosis is characterized by the splitting of sister chromatids and their movement to opposite poles?

Accepted Answer

Anaphase

Question 8

In plant cells, cytokinesis is accomplished by the formation of which structure?

Accepted Answer

Cell plate

Question 9

Which of the following is NOT a characteristic of cancer cells?

Accepted Answer

Density-dependent inhibition

Question 10

What is the role of cyclin-dependent kinases (cdks) in the cell cycle?

Accepted Answer

They are only active when bound to cyclin and regulate cell cycle progression

Question 11

A cell is observed to have a well-defined nucleus, nucleoli, duplicated chromatin, and two centrosomes. Which phase is it most likely in?

Accepted Answer

G2 phase

Question 12

Which of the following best explains why cells stop dividing when they form a single layer in culture?

Accepted Answer

Density-dependent inhibition

Question 13

Which of the following is a real-world example of external cues influencing cell division?

Accepted Answer

Fibroblasts dividing in response to platelet-derived growth factor (PDGF) during wound healing

Question 14

Which equation represents the relationship between cytoplasmic volume and genome size for actively dividing cells?

Accepted Answer

$	ext{Cytoplasmic Volume} \div 	ext{Genome Size} \geq 	ext{Critical Ratio}$

Question 15

Which of the following is true about the activity of MPF (maturation promoting factor) during the cell cycle?

Accepted Answer

MPF activity peaks during mitosis

Question 16

Which of the following best describes the process of metastasis?

Accepted Answer

Cancer cells invade neighboring tissue and spread to other parts of the body

Question 17

During which phase of mitosis do chromosomes align at the metaphase plate?

Accepted Answer

Metaphase

Question 18

Which of the following is a plausible consequence if a cell fails to pass the G1 checkpoint?

Accepted Answer

The cell will enter a non-dividing state called G0

Question 19

Which of the following best describes the difference between chromatin and chromosomes?

Accepted Answer

Chromatin is uncoiled DNA, chromosomes are condensed DNA seen during cell division

Question 20

Which of the following is a multi-step process that occurs during mitosis in animal cells?

Accepted Answer

Formation of a cleavage furrow, contractile ring, and separation into two cells

Cell Division and Regulation: Mitosis, Cell Cycle, and Cancer

Study Guide - Practice Questions