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Polygenic Inheritance, GWAS, and CRISPR Applications in Human Genetics

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Genes & Alleles

  • Genes & Alleles Example 1
    02:09
  • Genes & Alleles
    05:02
  • Haploid vs. Diploid Cells
    04:14

Genotype vs. Phenotype

  • Genotype & Phenotype
    06:36
  • Dominant vs. Recessive Alleles
    03:39

Introduction to Mendel's Experiments

  • Why Pea Plants?
    01:58
  • Introduction to Mendel's Experiments
    03:50

Non-Mendelian Genetics

  • Pleiotropy
    02:18
  • Multifactorial Characters
    01:39
  • Polygenic Inheritance
    02:27

Pedigrees

  • How to Read Pedigrees
    03:21
  • Pedigrees
    02:36

Introduction to DNA Replication

  • Unwinding the DNA: Topoisomerase, Helicase & SSBs
    05:10
  • Components of DNA Replication
    04:47
  • Origin of Replication
    03:33

Central Dogma

  • Central Dogma
    05:45

Introduction to Transcription

  • Overview of Transcription
    07:44
  • Introduction to Transcription
    05:51

Introduction to Types of RNA

  • Introduction to Types of RNA
    07:20

Introduction to Translation

  • Ribosomal tRNA Binding Sites
    06:16
  • Ribosome Subunits
    08:42
  • Introduction to Translation
    06:12

Mutations

  • Mutations
    02:29
  • Types of Mutations
    08:44

Introduction to Regulation of Gene Expression

  • Positive vs Negative Gene Regulation
    02:17
  • Introduction to Regulation of Gene Expression
    06:40

Prokaryotic Gene Regulation via Operons

  • Inducible Operons
    04:25
  • Prokaryotic Gene Regulation via Operons
    00:53
  • Repressible Operons
    03:42

The Lac Operon

  • In the Absence of Lactose
    04:34
  • The Lac Operon
    07:06
  • In the Presence of Lactose
    03:56

The Trp Operon

  • In the Presence of Tryptophan
    03:11
  • The Trp Operon
    05:30
  • In the Absence of Tryptophan
    03:42

Review of the Lac Operon & Trp Operon

  • Review of the Lac Operon & Trp Operon
    06:24

Introduction to Eukaryotic Gene Regulation

  • Map of Eukaryotic Gene Regulation
    04:22
  • Introduction to Eukaryotic Gene Regulation
    03:47

Eukaryotic Chromatin Modifications

  • Eukaryotic Chromatin Modifications
    03:55
  • Histone Acetylation
    04:14
  • DNA Methylation
    03:39

Eukaryotic Transcriptional Control

  • Introduction to Transcription Factors
    03:32
  • General Transcription Factors
    03:51
  • Specific Transcription Factors
    03:57

Eukaryotic Post-Transcriptional Regulation

  • Eukaryotic Post-Transcriptional Regulation
    01:56
  • 3) RNA Interference
    04:16
  • 1) Alternative RNA Splicing
    05:17

Eukaryotic Post-Translational Regulation

  • Protein Ubiquitination
    02:45
  • Eukaryotic Post-Translational Regulation
    03:55