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Ch. 9 The Endocrine System
Marieb - Essentials of Human Anatomy & Physiology 13th Edition
Marieb13th EditionEssentials of Human Anatomy & PhysiologyISBN: 9780135624340Non è quello che usi tu?Cambia libro di testo
Tutti i libri di testoMarieb 13th EditionCh. 9 The Endocrine SystemProblema 19
Capitolo 9, Problema 19

The parents of 14-year-old Megan are concerned about her height because she is only 4 feet tall and they are both close to 6 feet tall. After tests by their doctor, certain hormones are prescribed for the girl. What is the probable diagnosis? What hormones are prescribed, and why might the girl expect to reach normal height?

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The probable diagnosis is growth hormone deficiency (GHD), which occurs when the pituitary gland does not produce enough growth hormone (GH). This can result in stunted growth and delayed physical development.
The hormones prescribed are likely synthetic growth hormone (somatropin). This hormone mimics the natural growth hormone produced by the pituitary gland and stimulates growth in bones and tissues.
Growth hormone therapy works by promoting the growth of long bones through stimulation of the epiphyseal (growth) plates. These plates are still active in adolescents like Megan, allowing for potential height increase.
The doctor will likely monitor Megan's progress through regular check-ups, including measuring her height, assessing her growth rate, and possibly conducting blood tests to ensure the therapy is effective and safe.
If the therapy is started early enough and Megan's growth plates have not yet closed (a process that occurs after puberty), she can expect to achieve a height closer to her genetic potential, which is influenced by her parents' heights.

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Growth Hormone Deficiency

Growth hormone deficiency occurs when the pituitary gland does not produce enough growth hormone, which is essential for normal growth and development in children. This condition can lead to significantly shorter stature compared to peers, as seen in Megan's case. Diagnosis typically involves clinical evaluation and hormone level testing.
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Hormone Review Table Example 1

Hormonal Treatment

Hormonal treatment for growth issues often involves the administration of synthetic growth hormone. This therapy aims to stimulate growth in children with deficiencies, helping them achieve a height closer to their genetic potential. The effectiveness of this treatment depends on the timing and duration of therapy, as well as the underlying cause of the growth issue.
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Review of Major Hormones

Genetic Potential and Growth

Genetic potential refers to the height range that a child can achieve based on the heights of their parents and family history. If Megan's growth hormone treatment is successful, she may reach a height that aligns more closely with her genetic potential, despite her current short stature. Factors such as age, health, and adherence to treatment also play critical roles in determining growth outcomes.
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Genetic Code
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