a-student-claims-that-in-both-size-exclusion-chromatography-and-gel-electrophore

Question

A student claims that in both size exclusion chromatography and gel electrophoresis, smaller molecules elute first. How would you correct this misconception?

Accepted Answer

Explain that in size exclusion chromatography, larger molecules elute first due to their inability to enter the pores.

Answer

Agree with the student, as both techniques work the same way.

Answer

Explain that in both techniques, smaller molecules elute first due to their size.

Answer

Explain that in size exclusion chromatography, smaller molecules elute first due to their ability to enter the pores.