what-is-a-potential-limitation-of-size-exclusion-chromatography-in-protein-purif

Question

What is a potential limitation of size exclusion chromatography in protein purification?

Accepted Answer

It may not effectively separate proteins of very similar sizes.

Answer

It is ineffective for separating proteins of different shapes.

Answer

It cannot be used for proteins larger than the pore size.

Answer

It cannot separate proteins based on charge.