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Ch. 2 - Transmission Genetics
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Non è quello che usi tu?Cambia libro di testo
Capitolo 2, Problema 21a

The accompanying pedigree shows the transmission of a phenotypic character. Using B to represent a dominant allele and b to represent a recessive allele,
Pedigree chart illustrating the inheritance of a phenotypic trait with symbols for dominant and recessive alleles.
Give the genotype(s) possible for each member of the family, assuming the trait is autosomal dominant. 

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Examine the pedigree and identify individuals who express the autosomal dominant trait. These individuals must have at least one dominant allele (B).
Determine the genotype of individuals who do not express the trait. Since the trait is autosomal dominant, these individuals must be homozygous recessive (bb).
Analyze the inheritance pattern by considering the parents' genotypes and the phenotypes of their offspring. Use this information to deduce possible genotypes for each family member.
For individuals expressing the trait, consider whether they could be heterozygous (Bb) or homozygous dominant (BB). Use the offspring's phenotypes to narrow down the possibilities.
Assign possible genotypes (BB, Bb, or bb) to each family member based on the above analysis, ensuring consistency with the autosomal dominant inheritance pattern.

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Autosomal Dominance

Autosomal dominance refers to a pattern of inheritance where only one copy of a dominant allele is needed for the trait to be expressed. In this case, individuals with at least one 'B' allele will display the dominant phenotype, while those with two 'b' alleles will exhibit the recessive phenotype. This concept is crucial for analyzing pedigrees, as it helps determine the possible genotypes of family members based on their phenotypes.
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Variations on Dominance

Genotype vs. Phenotype

The genotype is the genetic makeup of an individual, represented by the alleles they possess (e.g., BB, Bb, or bb), while the phenotype is the observable expression of that genotype (e.g., dominant or recessive traits). Understanding the distinction between these two concepts is essential for interpreting the pedigree and deducing the genotypes of family members based on their phenotypic traits.
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Gamete Genotypes

Pedigree Analysis

Pedigree analysis is a method used to trace the inheritance of traits through generations in a family. It involves constructing a diagram that represents family relationships and the presence or absence of specific traits. By analyzing the patterns of inheritance shown in the pedigree, one can infer the possible genotypes of individuals, especially in the context of dominant and recessive traits.
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Pedigree Flowchart
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The accompanying pedigree shows the transmission of a phenotypic character. Using B to represent a dominant allele and b to represent a recessive allele,

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