Based on the information in Section 23.7, how would you expect each of these common metabolites to cross the cell membrane?
a. CO

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Understand the nature of the molecule: Carbon monoxide (CO) is a small, nonpolar molecule. Nonpolar molecules can typically diffuse across the lipid bilayer of the cell membrane without the need for transport proteins.

Recall the structure of the cell membrane: The cell membrane is composed of a phospholipid bilayer with hydrophobic (nonpolar) tails facing inward and hydrophilic (polar) heads facing outward. Nonpolar molecules like CO can pass through the hydrophobic core of the membrane.

Apply the principle of simple diffusion: Small, nonpolar molecules such as CO can cross the cell membrane via simple diffusion, which does not require energy or assistance from membrane proteins.

Consider the driving force for diffusion: The movement of CO across the membrane will depend on the concentration gradient. CO will diffuse from an area of higher concentration to an area of lower concentration until equilibrium is reached.

Summarize the process: CO crosses the cell membrane by simple diffusion due to its small size and nonpolar nature, moving along its concentration gradient without the need for energy or transport proteins.

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Cell Membrane Structure

The cell membrane is primarily composed of a phospholipid bilayer, which creates a semi-permeable barrier. This structure allows certain molecules to pass through while restricting others based on size, polarity, and charge. Understanding this structure is crucial for predicting how different metabolites, like CO, can traverse the membrane.

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Cell Membranes Example 1

Diffusion

Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. Small, nonpolar molecules, such as carbon monoxide (CO), can easily diffuse across the lipid bilayer of the cell membrane without the need for transport proteins, making this concept essential for understanding CO's movement.

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Oxidative Phosphorylation Example 1

Transport Mechanisms

Transport mechanisms refer to the various ways substances can cross the cell membrane, including passive transport (like diffusion) and active transport. While CO can diffuse passively, understanding other transport mechanisms is important for comparing how different metabolites might cross the membrane under various conditions.

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