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Ch. 16 - Adaptive Immunity
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Non è quello che usi tu?Cambia libro di testo
Capitolo 16, Problema 1a

Match each cell in the numbered list with its associated protein from the lettered list.
1. ___ Plasma cell
2. ___ Cytotoxic T cell
3. ___ Th2 cell
4. ___ Dendritic cell
A. MHC II molecule
B. Interleukin 4
C. Perforin and granzyme
D. Immunoglobulin

Guida verificata passo dopo passo
1
Step 1: Understand the function of each cell type listed. A plasma cell is a differentiated B cell that produces antibodies (immunoglobulins).
Step 2: Identify the protein associated with the plasma cell. Since plasma cells secrete antibodies, match it with Immunoglobulin (D).
Step 3: Consider the cytotoxic T cell, which kills infected or abnormal cells by releasing proteins that induce apoptosis.
Step 4: Match the cytotoxic T cell with Perforin and granzyme (C), the proteins it uses to destroy target cells.
Step 5: For the Th2 cell, which is a helper T cell subtype involved in stimulating B cells and producing cytokines, match it with Interleukin 4 (B), a key cytokine secreted by Th2 cells.

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Plasma Cells and Immunoglobulins

Plasma cells are differentiated B cells that produce and secrete large amounts of immunoglobulins (antibodies). These antibodies specifically recognize antigens and play a crucial role in humoral immunity by neutralizing pathogens or marking them for destruction.
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Naive B cells Become Effector (Plasma) Cells & Memory Cells

Cytotoxic T Cells and Cytotoxic Proteins

Cytotoxic T cells (CD8+ T cells) kill infected or abnormal cells by releasing cytotoxic proteins such as perforin and granzyme. Perforin forms pores in the target cell membrane, allowing granzymes to enter and induce apoptosis, effectively eliminating the threat.
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Review of Cytotoxic vs Helper T Cells

Th2 Cells, Interleukin 4, and MHC II Molecules

Th2 cells are a subset of helper T cells that secrete cytokines like interleukin 4 (IL-4), which promote B cell activation and antibody production. Dendritic cells present antigens to T cells using MHC II molecules, initiating the adaptive immune response by activating helper T cells.
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Classes of MHC Molecules