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Ch. 18 - Immune Disorders
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Non è quello che usi tu?Cambia libro di testo
Capitolo 18, Problema 10

What do medical personnel administer to counteract various type I hypersensitivities?
a. Antihistamine
b. Bronchodilator
c. Corticosteroid
d. Epinephrine
e. All of the above

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1
Understand that type I hypersensitivity reactions are immediate allergic reactions mediated by IgE antibodies, leading to the release of histamine and other mediators from mast cells and basophils.
Recognize that antihistamines (option a) are used to block histamine receptors, reducing symptoms like itching, swelling, and redness.
Know that bronchodilators (option b) help relax airway muscles, which is important in allergic asthma or anaphylaxis to improve breathing.
Identify that corticosteroids (option c) reduce inflammation and immune response, helping to control prolonged or severe allergic reactions.
Realize that epinephrine (option d) is the first-line treatment in severe anaphylaxis because it rapidly reverses airway constriction, reduces swelling, and supports blood pressure.
Conclude that medical personnel may administer all these treatments depending on the severity and symptoms of the type I hypersensitivity, making option e (all of the above) the comprehensive answer.

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Type I Hypersensitivity

Type I hypersensitivity is an immediate allergic reaction mediated by IgE antibodies. Upon exposure to an allergen, mast cells release histamine and other chemicals, causing symptoms like swelling, bronchoconstriction, and anaphylaxis.
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Antihistamines and Bronchodilators

Antihistamines block histamine receptors to reduce allergy symptoms such as itching and swelling. Bronchodilators relax airway muscles, improving breathing during allergic reactions like asthma.

Corticosteroids and Epinephrine

Corticosteroids reduce inflammation by suppressing immune responses, while epinephrine rapidly reverses severe allergic reactions by constricting blood vessels and opening airways, making it the first-line treatment for anaphylaxis.