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Ch. 17 - Skin and Eye Infections
Norman-McKay- Microbiology: Basic and Clinical Principles 2nd Edition
Norman-McKay2nd EditionMicrobiology: Basic and Clinical PrinciplesISBN: 9780137661619Non è quello che usi tu?Cambia libro di testo
Capitolo 13, Problema 13

Acanthamoeba protozoa species are associated with:
a. keratitis.
b. conjunctivitis.
c. river blindness.
d. trachoma.
e. all of the above.

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Step 1: Understand the organism in question. Acanthamoeba is a genus of free-living amoebae found in various environments such as soil, water, and air. It is known to cause infections in humans, particularly affecting the eyes and central nervous system.
Step 2: Review the diseases listed in the options and their common causative agents: keratitis (often caused by Acanthamoeba), conjunctivitis (commonly caused by bacteria or viruses), river blindness (caused by the parasitic worm Onchocerca volvulus), and trachoma (caused by Chlamydia trachomatis).
Step 3: Identify which disease(s) are specifically associated with Acanthamoeba. Acanthamoeba is well-known for causing keratitis, especially in contact lens users, due to its ability to invade the cornea.
Step 4: Evaluate the other options to confirm if Acanthamoeba is linked to them. Since conjunctivitis, river blindness, and trachoma have different primary causative agents, Acanthamoeba is not typically associated with these conditions.
Step 5: Conclude that the correct association is with keratitis, and therefore, the answer corresponds to option a.

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Acanthamoeba and Its Pathogenicity

Acanthamoeba is a genus of free-living amoebae found in soil and water. Some species are opportunistic pathogens causing infections in humans, particularly affecting the eyes and central nervous system. Understanding its pathogenic potential is key to linking it with specific diseases.
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Keratitis Caused by Acanthamoeba

Acanthamoeba keratitis is a serious eye infection affecting the cornea, often linked to contact lens use or exposure to contaminated water. It causes pain, redness, and potential vision loss, making it a hallmark disease associated with Acanthamoeba species.
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Differentiation from Other Eye Infections

Conjunctivitis, river blindness, and trachoma are caused by different pathogens: viruses/bacteria, Onchocerca volvulus, and Chlamydia trachomatis respectively. Recognizing these distinctions helps correctly associate Acanthamoeba specifically with keratitis.
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