what-is-the-role-of-beta-adrenergic-receptor-kinase-and-beta-arrestin-in-gpcr-de

Question

What is the role of beta adrenergic receptor kinase and beta arrestin in GPCR desensitization?

Accepted Answer

They phosphorylate and bind to GPCR, reducing its activity.

Answer

They inhibit the GDP to GTP exchange.

Answer

They increase the synthesis of cAMP.

Answer

They activate adenylate cyclase directly.