Question 1

Based on the first pedigree image, what pattern of inheritance does the trait most likely follow?

Accepted Answer

Autosomal recessive

Question 2

In the first pedigree, if the trait is autosomal recessive, what is the genotype of the affected individuals?

Accepted Answer

Homozygous recessive (aa)

Question 3

In the first pedigree, if the trait is autosomal recessive, what is the most likely genotype of the parents of the affected individual in the third generation?

Accepted Answer

Both are heterozygous

Question 4

In the second pedigree, what is the most likely mode of inheritance for the trait shown?

Accepted Answer

Autosomal dominant

Question 5

In the second pedigree, what is the genotype of individual 1 if the trait is autosomal dominant?

Accepted Answer

Heterozygous (Aa)

Question 6

In the second pedigree, what is the genotype of individual 2 if the trait is autosomal dominant and they are affected?

Accepted Answer

Heterozygous (Aa)

Question 7

In the second pedigree, what is the genotype of individual 3 if they are unaffected?

Accepted Answer

Homozygous recessive (aa)

Question 8

Which of the following best describes how you can distinguish between a dominant and recessive trait in a pedigree?

Accepted Answer

A dominant trait appears in every generation, while a recessive trait can skip generations

Question 9

If a trait is autosomal recessive, what is the probability that two heterozygous parents will have an affected child? Use the formula $$P = \frac{n_{affected}}{n_{total}}.$$

Accepted Answer

$$P = \frac{1}{4}$$

Question 10

If a trait is autosomal dominant, what is the probability that a heterozygous affected parent and an unaffected parent will have an affected child? Use the formula $$P = \frac{n_{affected}}{n_{total}}.$$

Accepted Answer

$$P = \frac{1}{2}$$

Patterns of Inheritance: Mendelian Genetics and Pedigree Analysis

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