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Anatomy & Physiology 1 - Chapter 2: Biological Chemistry

스터디 가이드 - 스마트 노트

자료에 맞춘 맞춤형 노트, 핵심 정의, 예시, 맥락을 확장해 제공합니다.

Body Cavities and Planes

Major Body Cavities

The human body contains several major cavities that house and protect internal organs. Understanding these cavities is fundamental to anatomical study.

  • Cranial Cavity: Contains the brain, protected by the skull.

  • Vertebral (Spinal) Cavity: Contains the spinal cord, protected by the vertebral column.

  • Thoracic Cavity: Contains the lungs and heart, divided into pleural, pericardial, and mediastinal regions.

  • Abdominopelvic Cavity: Contains digestive, urinary, and reproductive organs, further divided into abdominal and pelvic cavities.

Diagram of posterior and anterior body cavities

Anatomical Planes

Anatomical planes are imaginary lines used to divide the body for study and description.

  • Sagittal Plane: Divides the body into left and right sections.

  • Midsagittal Plane: Divides the body into equal left and right halves.

  • Frontal (Coronal) Plane: Divides the body into anterior (front) and posterior (back) sections.

  • Transverse Plane: Divides the body into superior (upper) and inferior (lower) sections.

Biological Chemistry

Elements in the Human Body

Elements are pure substances that cannot be broken down by chemical means. The human body is composed primarily of four major elements, with several mineral and trace elements contributing to physiological functions.

  • Major Elements: Oxygen (O), Carbon (C), Hydrogen (H), Nitrogen (N)

  • Mineral Elements: Sodium (Na), Potassium (K), Calcium (Ca), Chlorine (Cl), Magnesium (Mg), Phosphorus (P), Sulfur (S)

  • Trace Elements: Iron (Fe), Copper (Cu), Iodine (I), Zinc (Zn), and others

Periodic table highlighting elements in the human body

Atomic Structure

An atom consists of a nucleus containing protons and neutrons, surrounded by electrons in shells. The atomic number is determined by the number of protons.

  • Protons: Positively charged particles

  • Neutrons: Neutral particles

  • Electrons: Negatively charged particles

  • Valence Electrons: Electrons in the outermost shell, important for chemical bonding

Diagram of a carbon atom showing nucleus and electron shells

Electron Shells and Stability

Atoms are most stable when their valence shell is full. The octet rule states that atoms are stable with eight electrons in their valence shell, while the duet rule applies to atoms with only two electrons in their first shell.

Chemical Bonds

Chemical bonds form when atoms interact to achieve stability. The main types are ionic, covalent, and hydrogen bonds.

  • Ionic Bonds: Formed by transfer of electrons, resulting in charged ions (cations and anions)

  • Covalent Bonds: Formed by sharing electrons between atoms

  • Polar Covalent Bonds: Unequal sharing of electrons, creating partial charges

  • Nonpolar Covalent Bonds: Equal sharing of electrons

Comparison of polar and nonpolar covalent bonds

Hydrogen Bonds

Hydrogen bonds are weak attractions between the partial positive charge of hydrogen and the partial negative charge of another atom, often oxygen or nitrogen. They are crucial for the properties of water and the structure of biological molecules.

Hydrogen bonds between water molecules

Mixtures in the Human Body

Mixtures are combinations of substances physically intermixed. The three main types are suspensions, colloids, and solutions.

  • Suspensions: Large particles settle out (e.g., blood)

  • Colloids: Small particles do not settle out (e.g., milk)

  • Solutions: Solute dissolves in solvent, usually water (e.g., sugar water)

Examples of suspension, colloid, and solution

Properties of Water

Water is essential for life due to its unique properties:

  • Absorbs heat without significant temperature change

  • Carries heat during evaporation

  • Cushions and protects organs

  • Acts as a lubricant

Hydrophilic vs. Hydrophobic Compounds

Compounds interact with water based on their polarity:

  • Hydrophilic: Water-loving; ionic and polar covalent compounds dissolve in water

  • Hydrophobic: Water-fearing; nonpolar covalent compounds do not dissolve in water

Hydrophilic and hydrophobic compounds in water

Acids, Bases, and pH

Acids donate hydrogen ions (H+), while bases accept them. The pH scale measures the concentration of H+ ions, ranging from 0 (acidic) to 14 (basic). Buffers help maintain stable pH in the body.

  • Acid: H+ donor

  • Base: H+ acceptor

  • Buffer: Resists changes in pH

Acids and bases in solution pH scale

Organic Molecules

Carbohydrates

Carbohydrates are hydrophilic molecules composed of monosaccharides (monomers), disaccharides, and polysaccharides (polymers). They serve as energy sources and structural components.

  • Monosaccharides: Simple sugars (e.g., glucose)

  • Disaccharides: Two monosaccharides linked (e.g., sucrose)

  • Polysaccharides: Chains of monosaccharides (e.g., glycogen)

Monosaccharide structures Disaccharide formation Polysaccharide structure

Lipids

Lipids are hydrophobic molecules, including fatty acids, triglycerides, phospholipids, and steroids. They function in energy storage, membrane structure, and signaling.

  • Fatty Acids: Monomers; can be saturated, monounsaturated, or polyunsaturated

  • Triglycerides: Three fatty acids bonded to glycerol; main fat storage form

  • Phospholipids: Amphiphilic molecules forming cell membranes

  • Steroids: Four-ring structure; includes cholesterol and hormones

Fatty acid types Triglyceride formation Phospholipid structure Steroid structure

Proteins

Proteins are polymers of amino acids, folded into specific structures for diverse functions such as enzymes, hormones, and structural components.

  • Amino Acids: Monomers; each has a unique R group

  • Peptides: Short chains of amino acids

  • Polypeptides: Long chains; fold into fibrous or globular proteins

Amino acid structure Peptide bond formation Protein structure levels

Nucleic Acids

Nucleic acids are polymers of nucleotides, essential for genetic information storage and transfer. DNA and RNA are the two main types.

  • Nucleotides: Monomers composed of a phosphate group, pentose sugar, and nitrogenous base

  • DNA: Double helix; stores genetic information

  • RNA: Single strand; involved in protein synthesis

Nucleotide structure DNA and RNA structure

Adenosine Triphosphate (ATP)

ATP is the primary energy carrier in cells. Energy is stored by adding a phosphate group to ADP, forming ATP.

  • ATP: Three phosphate groups; stores energy

  • ADP: Two phosphate groups; can be converted to ATP

ATP structure and energy storage

Table: Overview of Major Organic Compounds

Type

Monomer

Polymer

Function

Example

Carbohydrates

Monosaccharide

Polysaccharide

Energy, structure

Glucose, glycogen

Lipids

Fatty acid

Triglyceride, phospholipid

Energy storage, membrane

Triglyceride, cholesterol

Proteins

Amino acid

Polypeptide

Enzymes, structure

Hemoglobin, collagen

Nucleic Acids

Nucleotide

DNA, RNA

Genetic information

DNA, RNA

Sample Review Questions

  • Which organ system is responsible for protecting the body from disease? Lymphatic System

  • Which plane divides the body into superior and inferior sections? Transverse Plane

  • Name the body cavity shown in the diagram. Cranial Cavity and Thoracic Cavity (see image_1)

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