뒤로General Biology Exam 1 Study Guide: Foundations, Chemistry of Life, and Macromolecules
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Concepts to Know and Understand
Seven Properties of Life and Hierarchy of Organization
Biology is the study of living organisms, which share certain properties and are organized in a hierarchical manner.
Properties of Life: Living things exhibit order, regulation, growth and development, energy processing, response to the environment, reproduction, and evolutionary adaptation.
Hierarchy of Organization: Life is organized from the smallest to largest as follows: molecule → organelle → cell → tissue → organ → organ system → organism → population → community → ecosystem → biosphere.
Example: A human is an organism, made up of organ systems, which are made of organs, and so on down to molecules.
Scientific Process: Hypotheses, Theories, and Experiments
The scientific method is a systematic approach to understanding the natural world.
Hypothesis: A testable, falsifiable explanation for an observation.
Theory: A broad, well-supported explanation for a wide range of phenomena.
Controlled Experiment: An experiment in which only one variable is changed at a time.
Variables: Independent variable (manipulated), dependent variable (measured), controlled variables (kept constant).
Observational Data/Experiments: Data collected without manipulation, often used in field studies.
Elements, Atoms, and Compounds
All matter is composed of elements, which combine to form compounds essential for life.
Element: A substance that cannot be broken down into simpler substances by chemical means.
Atom: The smallest unit of an element, consisting of protons, neutrons, and electrons.
Atomic Number: Number of protons in an atom.
Mass Number: Number of protons plus neutrons.
Isotopes: Atoms of the same element with different numbers of neutrons; some are radioactive.
Trace Elements: Elements required in very small amounts but essential for life (e.g., iron, iodine).
Chemical Bonds
Atoms combine through chemical bonds to form molecules and compounds.
Ionic Bond: Formed when electrons are transferred from one atom to another, resulting in oppositely charged ions.
Covalent Bond: Formed when two atoms share one or more pairs of electrons.
How to Draw: Use Lewis dot structures to represent valence electrons and bonding.
Unique Features: Ionic bonds create charged ions; covalent bonds create stable molecules.
Water: Properties and Importance
Water is essential for life due to its unique chemical and physical properties.
Polarity: Water is a polar molecule, with partial positive and negative charges.
Hydrogen Bonding: Weak bonds between the hydrogen of one water molecule and the oxygen of another.
Cohesion and Adhesion: Cohesion is the attraction between water molecules; adhesion is attraction to other substances.
Surface Tension: The result of cohesion at the surface of water.
High Specific Heat and Evaporative Cooling: Water resists temperature change and cools surfaces as it evaporates.
Solvent Properties: Water dissolves many substances, making it the "universal solvent." Equation:
Acids, Bases, and pH
Acids and bases are substances that alter the hydrogen ion concentration in solutions.
Acid: Substance that increases the concentration of H+ ions in solution.
Base: Substance that decreases the concentration of H+ ions (or increases OH-).
pH Scale: Measures hydrogen ion concentration; ranges from 0 (acidic) to 14 (basic), with 7 as neutral.
Equation:
Buffers: Substances that minimize changes in pH.
Organic Molecules and Functional Groups
Organic molecules are carbon-based and form the basis of life. Functional groups determine their properties.
Hydrocarbons: Molecules consisting only of carbon and hydrogen.
Functional Groups: Specific groups of atoms that confer characteristic properties (e.g., -OH, -COOH, -NH2, -PO42-).
Isomers: Molecules with the same formula but different structures.
Macromolecules: Carbohydrates, Lipids, Proteins
Macromolecules are large, complex molecules essential for life. They are built from smaller subunits.
Carbohydrates
Monosaccharides: Simple sugars (e.g., glucose, fructose).
Disaccharides: Two monosaccharides joined by a glycosidic bond (e.g., sucrose).
Polysaccharides: Long chains of monosaccharides (e.g., starch, glycogen, cellulose).
Function: Energy storage and structural support.
Dehydration Reaction: Joins monomers by removing water.
Hydrolysis: Breaks polymers into monomers by adding water.
Lipids
General Characteristics: Hydrophobic molecules, including fats, phospholipids, and steroids.
Fats: Composed of glycerol and fatty acids; used for energy storage.
Saturated vs. Unsaturated Fatty Acids: Saturated have no double bonds; unsaturated have one or more double bonds.
Steroids: Lipids with a four-ring structure (e.g., cholesterol).
Phospholipids: Major component of cell membranes; have hydrophilic heads and hydrophobic tails.
Proteins
General Characteristics: Polymers of amino acids; perform a wide range of functions.
Amino Acid Structure: Central carbon, amino group (-NH2), carboxyl group (-COOH), hydrogen, and R group.
Peptide Bonds: Link amino acids to form polypeptides.
Levels of Structure: Primary (sequence), secondary (alpha helix, beta sheet), tertiary (3D folding), quaternary (multiple polypeptides).
Denaturation: Loss of protein structure and function due to environmental changes.
Table: Comparison of Macromolecules
Macromolecule | Monomer | Bond Type | Main Functions |
|---|---|---|---|
Carbohydrates | Monosaccharide | Glycosidic bond | Energy storage, structure |
Lipids | Glycerol & Fatty acids | Ester bond | Energy storage, membranes, signaling |
Proteins | Amino acid | Peptide bond | Catalysis, structure, transport, signaling |
Additional info:
Be able to identify macromolecules by their structure and know their general functions.
Review the differences between polar and nonpolar covalent bonds, and the significance of hydrophobic vs. hydrophilic molecules.
Practice drawing and interpreting basic chemical structures and reactions.