a-protein-with-a-mutated-er-retention-signal-is-found-in-the-golgi-apparatus-wha

Question

A protein with a mutated ER retention signal is found in the Golgi apparatus. What is the most likely reason for this mislocalization?

Accepted Answer

The mutated retention signal failed to retain the protein in the ER, allowing it to be transported to the Golgi.

Answer

The protein lacked a start transfer sequence, preventing its insertion into the ER membrane.

Answer

The protein was misfolded and degraded by ERAD proteins.

Answer

The protein was glycosylated incorrectly, leading to its transport to the Golgi.