검증된 단계별 안내
11:19
07:58
05:05A short RNA molecule was isolated that demonstrated a hyperchromic shift, indicating secondary structure. Its sequence was determined to be
5'-AGGCGCCGACUCUACU-3'
If the molecule were an internal part of a message, what amino acid sequence would result from it following translation?
Refer to the genetic coding dictionary to respond to the following:
A base-substitution mutation that altered the sequence shown in part (a) eliminated the synthesis of all but one polypeptide. The altered sequence is shown here:
5'-AUGCAUACCUAUGUGACCCUUGGA-3'
Determine why.
Define the process of transcription. Where does this process fit into the central dogma of molecular biology (DNA makes RNA makes protein)?
Most proteins have more leucine than histidine residues, but more histidine than tryptophan residues. Correlate the number of codons for these three amino acids with this information.
A glycine residue is in position 210 of the tryptophan synthetase enzyme of wild-type E. coli. If the codon specifying glycine is GGA, how many single-base substitutions will result in an amino acid substitution at position 210? What are they? How many will result if the wild-type codon is GGU?
A short RNA molecule was isolated that demonstrated a hyperchromic shift, indicating secondary structure. Its sequence was determined to be
5'-AGGCGCCGACUCUACU-3'
If the molecule were a tRNA fragment containing a CGA anticodon, what would the corresponding codon be?
