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Ch. 10 - Eukaryotic Chromosome Abnormalities and Molecular Organization
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
10장, 문제 12a

A pair of homologous chromosomes in Drosophila has the following content (single letters represent genes):
Chromosome 1RNMDHBGKWU
Chromosome 2RNMDHBDHBGKWU
What term best describes this situation?

검증된 단계별 안내
1
Step 1: Begin by comparing the gene sequences of Chromosome 1 and Chromosome 2. Chromosome 1 has the sequence RNMDHBGKWU, while Chromosome 2 has the sequence RNMDHBDHBGKWU.
Step 2: Identify any differences between the two sequences. Notice that Chromosome 2 contains an extra segment 'DHBG' inserted between the genes 'H' and 'G'.
Step 3: Understand the concept of duplication in genetics. Duplication occurs when a segment of DNA is copied and inserted into the genome, resulting in repeated sequences.
Step 4: Recognize that the presence of the duplicated segment 'DHBG' in Chromosome 2 is a clear example of a duplication event.
Step 5: Conclude that the term best describing this situation is 'duplication,' as it refers to the repeated segment of genes in Chromosome 2 compared to Chromosome 1.

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이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
2m

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Homologous Chromosomes

Homologous chromosomes are pairs of chromosomes in a diploid organism that have the same structure and gene sequence but may carry different alleles. Each parent contributes one chromosome to the pair, resulting in genetic variation. In the context of Drosophila, these chromosomes can carry genes that influence traits, and their comparison can reveal important genetic relationships.
추천 영상:
가이드 코스
07:10
Chromosome Structure

Alleles

Alleles are different versions of a gene that can exist at a specific locus on a chromosome. They can be dominant or recessive, influencing the phenotype of an organism. In the given example, the presence of different alleles on the homologous chromosomes can lead to variations in traits among offspring, highlighting the importance of allele diversity in genetics.
추천 영상:
가이드 코스
03:03
New Alleles and Migration

Genetic Variation

Genetic variation refers to the diversity in gene frequencies within a population. It is crucial for evolution and adaptation, as it provides the raw material for natural selection. The differences in the gene sequences of the homologous chromosomes in Drosophila suggest the presence of genetic variation, which can affect the traits expressed in the organism.
추천 영상:
가이드 코스
09:28
Genomic Variation
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교과서 질문

A pair of homologous chromosomes in Drosophila has the following content (single letters represent genes):

Chromosome 1RNMDHBGKWU

Chromosome 2RNMDHBDHBGKWU

What term best describes the unusual structure that forms during pairing of these chromosomes?

434
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교과서 질문

A pair of homologous chromosomes in Drosophila has the following content (single letters represent genes):

Chromosome 1RNMDHBGKWU

Chromosome 2RNMDHBDHBGKWU

Diagram the pairing of these homologous chromosomes in prophase I.

384
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교과서 질문

The most common reason a physician might recommend that a woman have maternal serum screening and a karyotype analysis is concern that her fetus may have Down syndrome. Go to the OMIM website at www.ncbi.nlm.nih.gov/omim and look up Down syndrome (OMIM 190685).

How might those genes lead to the main symptoms of Down syndrome?

525
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교과서 질문

The most common reason a physician might recommend that a woman have maternal serum screening and a karyotype analysis is concern that her fetus may have Down syndrome. Go to the OMIM website at www.ncbi.nlm.nih.gov/omim and look up Down syndrome (OMIM 190685).

Look at the 'Mapping' and 'Molecular Genetics' sections and describe what is meant by the Down syndrome critical region (DSCR).

552
views
교과서 질문

A pair of homologous chromosomes in Drosophila has the following content (single letters represent genes):

Chromosome 1RNMDHBGKWU

Chromosome 2RNMDHBDHBGKWU

How does the pairing diagrammed in part (b) differ from the pairing of chromosomes in an inversion heterozygote?

425
views
교과서 질문

The most common reason a physician might recommend that a woman have maternal serum screening and a karyotype analysis is concern that her fetus may have Down syndrome. Go to the OMIM website at www.ncbi.nlm.nih.gov/omim and look up Down syndrome (OMIM 190685).

Summarize what is known about the location and genes found within the DSCR.

450
views