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Ch. 4 - Gene Interaction
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
4장, 문제 38a

Draw a pedigree containing two parents and four children. Both of the parents have AB blood type. The first child is type A, the second child is type AB, and the third child is type B.


Assign the genotypes to these five people.

검증된 단계별 안내
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Start by understanding the ABO blood group system. Blood type is determined by the ABO gene, which has three alleles: IA, IB, and i. IA and IB are codominant, meaning both are expressed when present together, while i is recessive.
Assign the genotypes of the parents. Since both parents have AB blood type, their genotypes must be IAIB. This means each parent can pass on either the IA or IB allele to their offspring.
Determine the possible genotypes of the children. Use a Punnett square to cross the IAIB genotypes of the parents. The possible combinations are: IAIA (Type A), IAIB (Type AB), IBIB (Type B), and IAi or IBi (Type A or B, but i is not relevant here since all children have A, AB, or B types).
Assign the genotypes to the children based on their blood types: - The first child is Type A, so their genotype must be IAIA. - The second child is Type AB, so their genotype must be IAIB. - The third child is Type B, so their genotype must be IBIB.
Draw the pedigree. Represent the parents as a male (square) and female (circle) connected by a horizontal line. Below them, draw four vertical lines leading to the children (circles or squares depending on gender). Label each individual with their blood type and genotype: Parents (IAIB), First child (IAIA), Second child (IAIB), Third child (IBIB).

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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Blood Type Inheritance

Blood type is determined by the ABO gene, which has three alleles: A, B, and O. The A and B alleles are co-dominant, meaning that if both are present, the individual will have type AB blood. The O allele is recessive, so an individual must inherit two O alleles to have type O blood. Understanding these inheritance patterns is crucial for predicting the blood types of offspring based on parental genotypes.
추천 영상:
가이드 코스
00:36
Types of Maternal Inheritance

Genotype and Phenotype

The genotype refers to the genetic makeup of an individual, while the phenotype is the observable expression of that genotype. For blood types, the genotype can be AA, AO, BB, BO, AB, or OO, which correspond to the phenotypes A, B, AB, and O. Knowing the genotypes of the parents allows us to predict the possible phenotypes of their children.
추천 영상:
가이드 코스
07:52
Gamete Genotypes

Pedigree Analysis

A pedigree is a diagram that depicts the genetic relationships and inheritance patterns within a family. It uses standardized symbols to represent individuals and their phenotypes, allowing for the visualization of how traits are passed down through generations. Analyzing a pedigree helps in understanding the likelihood of certain traits appearing in offspring based on the genotypes of the parents.
추천 영상:
가이드 코스
01:59
Pedigree Flowchart