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Ch. 7 - DNA Structure and Replication
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
모든 교과서Sanders 3rd EditionCh. 7 - DNA Structure and Replication문제 13
7장, 문제 13

A sample of double-stranded DNA is found to contain 20% cytosine. Determine the percentage of the three other DNA nucleotides in the sample.

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1
Understand the base-pairing rules in DNA: Cytosine (C) pairs with Guanine (G), and Adenine (A) pairs with Thymine (T). This means the percentage of cytosine equals the percentage of guanine in the DNA sample.
Since the DNA is double-stranded, the total percentage of all four nucleotides (C, G, A, T) must add up to 100%.
Given that cytosine (C) makes up 20% of the DNA, guanine (G) must also make up 20% because of the base-pairing rule. Together, cytosine and guanine account for 40% of the DNA.
Subtract the combined percentage of cytosine and guanine (40%) from 100% to determine the combined percentage of adenine (A) and thymine (T).
Divide the remaining percentage equally between adenine (A) and thymine (T), as they pair with each other in equal amounts in double-stranded DNA.

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주요 개념

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Base Pairing Rules

In DNA, the base pairing rules dictate that adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). This means that the amount of adenine will equal the amount of thymine, and the amount of cytosine will equal the amount of guanine in a double-stranded DNA molecule. Understanding these rules is essential for calculating the percentages of the nucleotides based on the given information.
추천 영상:
가이드 코스
03:49
Base Distortions

Complementary Base Pairing

Complementary base pairing refers to the specific pairing of nitrogenous bases in DNA. Since the sample contains 20% cytosine, it must also contain 20% guanine due to their complementary relationship. This concept is crucial for determining the percentages of the other nucleotides in the DNA sample.
추천 영상:
가이드 코스
03:49
Base Distortions

Percentage Composition of DNA

The percentage composition of DNA nucleotides can be calculated by knowing the total percentage must equal 100%. Given that cytosine and guanine each account for 20%, the remaining percentage (60%) must be divided equally between adenine and thymine, leading to each being 30%. This concept is fundamental for solving the problem presented.
추천 영상:
가이드 코스
01:45
DNA Proofreading
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