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Ch. 7 - DNA Structure and Replication
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
7장, 문제 16e

Which of the following equations are true for the percentages of nucleotides in double-stranded DNA?
(A)/(G)=(T)(C)

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Understand the context: In double-stranded DNA, the base pairing rules (Chargaff's rules) state that adenine (A) pairs with thymine (T) and guanine (G) pairs with cytosine (C). This means the amount of A equals T, and the amount of G equals C.
Analyze the given equation: The equation provided is (A)/(G) = (T)(C). This equation suggests a relationship between the percentages of the nucleotides in double-stranded DNA.
Check the left-hand side of the equation: The term (A)/(G) represents the ratio of adenine to guanine. According to Chargaff's rules, there is no direct proportionality between A and G, as A pairs with T and G pairs with C.
Check the right-hand side of the equation: The term (T)(C) represents the product of the percentages of thymine and cytosine. Again, there is no direct relationship between T and C in terms of multiplication, as T pairs with A and C pairs with G.
Conclude the validity of the equation: Based on Chargaff's rules, the equation (A)/(G) = (T)(C) does not hold true for double-stranded DNA. The relationships between nucleotide percentages are A = T and G = C, not the given equation.

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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Chargaff's Rules

Chargaff's Rules state that in double-stranded DNA, the amount of adenine (A) equals thymine (T), and the amount of guanine (G) equals cytosine (C). This means that A pairs with T and G pairs with C, leading to a specific ratio of these nucleotides in the DNA structure. Understanding these rules is essential for analyzing nucleotide percentages.
추천 영상:
가이드 코스
08:44
Genetics Basics

Base Pairing

Base pairing refers to the specific hydrogen bonding between nucleotides in DNA, where adenine pairs with thymine and guanine pairs with cytosine. This complementary pairing is crucial for the stability of the DNA double helix and ensures accurate replication and transcription. Recognizing base pairing is vital for interpreting nucleotide ratios.
추천 영상:
가이드 코스
03:49
Base Distortions

Nucleotide Composition

Nucleotide composition in DNA refers to the relative amounts of the four nucleotides: adenine, thymine, guanine, and cytosine. In double-stranded DNA, the total percentage of A and T should equal that of G and C due to base pairing. This composition is fundamental for understanding the equations related to nucleotide percentages.
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가이드 코스
06:51
Human Genome Composition